Bone-immune cell crosstalk: bone diseases.

Details

Serval ID
serval:BIB_2E708B34DB8F
Type
Article: article from journal or magazin.
Collection
Publications
Title
Bone-immune cell crosstalk: bone diseases.
Journal
Journal of immunology research
Author(s)
Mori G., D'Amelio P., Faccio R., Brunetti G.
ISSN
2314-7156 (Electronic)
ISSN-L
2314-7156
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
2015
Pages
108451
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Bone diseases are associated with great morbidity; thus, the understanding of the mechanisms leading to their development represents a great challenge to improve bone health. Recent reports suggest that a large number of molecules produced by immune cells affect bone cell activity. However, the mechanisms are incompletely understood. This review aims to shed new lights into the mechanisms of bone diseases involving immune cells. In particular, we focused our attention on the major pathogenic mechanism underlying periodontal disease, psoriatic arthritis, postmenopausal osteoporosis, glucocorticoid-induced osteoporosis, metastatic solid tumors, and multiple myeloma.
Keywords
B-Lymphocytes/immunology, Bone Density/immunology, Bone Diseases/immunology, Bone Diseases/pathology, Bone Remodeling/physiology, Bone and Bones/immunology, Bone and Bones/pathology, Cytokines/immunology, Humans, Inflammation/immunology, Th1 Cells/immunology, Th17 Cells/immunology, Th2 Cells/immunology
Pubmed
Web of science
Open Access
Yes
Create date
14/01/2020 7:56
Last modification date
15/01/2020 6:26
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