Patterns of alcohol consumption and acute myocardial infarction: a case-crossover analysis.

Details

Serval ID
serval:BIB_2E57ED1AB036
Type
Article: article from journal or magazin.
Collection
Publications
Title
Patterns of alcohol consumption and acute myocardial infarction: a case-crossover analysis.
Journal
European Addiction Research
Author(s)
Gerlich M.G., Krämer A., Gmel G., Maggiorini M., Lüscher T.F., Rickli H., Kleger G.R., Rehm J.
ISSN
1421-9891[electronic]
Publication state
Published
Issued date
2009
Volume
15
Number
3
Pages
143-149
Language
english
Abstract
BACKGROUND: Alcohol consumption has been causally related to the incidence of coronary heart disease, but the role of alcohol before the event has not been explored in depth. This study tested the hypothesis that heavy drinking (binge drinking) increases the risk of subsequent acute myocardial infarctions (AMI), whereas light to moderate drinking occasions decrease the risk. METHODS: Case-crossover design of 250 incident AMI cases in Switzerland, with main hypotheses tested by conditional logistic regression. RESULTS: Alcohol consumption 12 h before the event significantly increased the risk of AMI (OR 3.1; 95% CI 1.4-6.9). Separately, the effects of moderate and binge drinking before the event on AMI were of similar size but did not reach significance. In addition, AMI patients showed more binge drinking than comparable control subjects from the Swiss general population. CONCLUSIONS: We found no evidence that alcohol consumption before the event had protective effects on AMI. Instead, alcohol consumption increased the risk.
Pubmed
Web of science
Create date
20/01/2010 16:19
Last modification date
20/08/2019 13:12
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