The Impact of the COVID-19 Pandemic and Associated Control Measures on the Mental Health of the General Population : A Systematic Review and Dose-Response Meta-analysis.
Details
Serval ID
serval:BIB_2DBEBF741ABB
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The Impact of the COVID-19 Pandemic and Associated Control Measures on the Mental Health of the General Population : A Systematic Review and Dose-Response Meta-analysis.
Journal
Annals of internal medicine
Working group(s)
MHCOVID Crowd Investigators, MHCOVID Crowd Investigators†
Contributor(s)
Sambo A.U., Onishi A., Sato A., Rodolico A., Oliveira Solis A.C., Antoniou A., Kapfhammer A., Ceraso A., O'Mahony A., Lasserre A.M., Ipekci A.M., Concerto C., Zangani C., Igwesi-Chidobe C., Diehm C., Demir D.D., Wang D., Ostinelli E.G., Sahker E., Beraldi G.H., Erzin G., Nelson H., Elkis H., Imai H., Wu H., Kamitsis I., Filis I., Michopoulos I., Bighelli I., Hong JSW, Ballesteros J., Smith K.A., Yoshida K., Omae K., Trivella M., Tada M., Reinhard M.A., Ostacher M.J., Müller M., Jaramillo N.G., Ferentinos P.P., Toyomoto R., Cortese S., Kishimoto S., Covarrubias-Castillo S.A., Siafis S., Thompson T., Karageorgiou V., Chiocchia V., Zhu Y., Honda Y.
ISSN
1539-3704 (Electronic)
ISSN-L
0003-4819
Publication state
Published
Issued date
11/2022
Peer-reviewed
Oui
Volume
175
Number
11
Pages
1560-1571
Language
english
Notes
Publication types: Journal Article ; Meta-Analysis ; Systematic Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
To what extent the COVID-19 pandemic and its containment measures influenced mental health in the general population is still unclear.
To assess the trajectory of mental health symptoms during the first year of the pandemic and examine dose-response relations with characteristics of the pandemic and its containment.
Relevant articles were identified from the living evidence database of the COVID-19 Open Access Project, which indexes COVID-19-related publications from MEDLINE via PubMed, Embase via Ovid, and PsycInfo. Preprint publications were not considered.
Longitudinal studies that reported data on the general population's mental health using validated scales and that were published before 31 March 2021 were eligible.
An international crowd of 109 trained reviewers screened references and extracted study characteristics, participant characteristics, and symptom scores at each timepoint. Data were also included for the following country-specific variables: days since the first case of SARS-CoV-2 infection, the stringency of governmental containment measures, and the cumulative numbers of cases and deaths.
In a total of 43 studies (331 628 participants), changes in symptoms of psychological distress, sleep disturbances, and mental well-being varied substantially across studies. On average, depression and anxiety symptoms worsened in the first 2 months of the pandemic (standardized mean difference at 60 days, -0.39 [95% credible interval, -0.76 to -0.03]); thereafter, the trajectories were heterogeneous. There was a linear association of worsening depression and anxiety with increasing numbers of reported cases of SARS-CoV-2 infection and increasing stringency in governmental measures. Gender, age, country, deprivation, inequalities, risk of bias, and study design did not modify these associations.
The certainty of the evidence was low because of the high risk of bias in included studies and the large amount of heterogeneity. Stringency measures and surges in cases were strongly correlated and changed over time. The observed associations should not be interpreted as causal relationships.
Although an initial increase in average symptoms of depression and anxiety and an association between higher numbers of reported cases and more stringent measures were found, changes in mental health symptoms varied substantially across studies after the first 2 months of the pandemic. This suggests that different populations responded differently to the psychological stress generated by the pandemic and its containment measures.
Swiss National Science Foundation. (PROSPERO: CRD42020180049).
To assess the trajectory of mental health symptoms during the first year of the pandemic and examine dose-response relations with characteristics of the pandemic and its containment.
Relevant articles were identified from the living evidence database of the COVID-19 Open Access Project, which indexes COVID-19-related publications from MEDLINE via PubMed, Embase via Ovid, and PsycInfo. Preprint publications were not considered.
Longitudinal studies that reported data on the general population's mental health using validated scales and that were published before 31 March 2021 were eligible.
An international crowd of 109 trained reviewers screened references and extracted study characteristics, participant characteristics, and symptom scores at each timepoint. Data were also included for the following country-specific variables: days since the first case of SARS-CoV-2 infection, the stringency of governmental containment measures, and the cumulative numbers of cases and deaths.
In a total of 43 studies (331 628 participants), changes in symptoms of psychological distress, sleep disturbances, and mental well-being varied substantially across studies. On average, depression and anxiety symptoms worsened in the first 2 months of the pandemic (standardized mean difference at 60 days, -0.39 [95% credible interval, -0.76 to -0.03]); thereafter, the trajectories were heterogeneous. There was a linear association of worsening depression and anxiety with increasing numbers of reported cases of SARS-CoV-2 infection and increasing stringency in governmental measures. Gender, age, country, deprivation, inequalities, risk of bias, and study design did not modify these associations.
The certainty of the evidence was low because of the high risk of bias in included studies and the large amount of heterogeneity. Stringency measures and surges in cases were strongly correlated and changed over time. The observed associations should not be interpreted as causal relationships.
Although an initial increase in average symptoms of depression and anxiety and an association between higher numbers of reported cases and more stringent measures were found, changes in mental health symptoms varied substantially across studies after the first 2 months of the pandemic. This suggests that different populations responded differently to the psychological stress generated by the pandemic and its containment measures.
Swiss National Science Foundation. (PROSPERO: CRD42020180049).
Keywords
Humans, Anxiety/epidemiology, Anxiety/psychology, COVID-19/epidemiology, Depression/psychology, Mental Health, Pandemics, SARS-CoV-2
Pubmed
Web of science
Create date
22/11/2022 13:19
Last modification date
23/11/2022 7:52
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