Interferon-Produktion bei der akuten Virushepatitis [Interferon production in acute virus hepatitis].

Details

Serval ID
serval:BIB_2D3A358DD4A5
Type
Article: article from journal or magazin.
Collection
Publications
Title
Interferon-Produktion bei der akuten Virushepatitis [Interferon production in acute virus hepatitis].
Journal
Leber, Magen, Darm
Author(s)
Pirovino M., Aguet M., Huber M., Altorfer J., Schmid M.
ISSN
0300-8622 (Print)
ISSN-L
0300-8622
Publication state
Published
Issued date
1984
Volume
14
Number
6
Pages
258-260
Language
german
Notes
Publication types: English Abstract ; Journal Article
Abstract
Serum interferon activity was measured in 40 patients with acute viral hepatitis A, B and non-A-non-B during the acute stage of the disease and correlated with the severity, the long-term outcome and the viral etiology of the disease. Patients with alcoholic hepatitis, patients with an influenza-like illness and healthy volunteers served as controls. 80% of all patients with virus hepatitis revealed no measureable or only borderline interferon activity in their serum. No correlation was found with severity and long-term outcome of the disease, but patients with virus hepatitis A showed a stronger interferon induction than patients with hepatitis B and non-A-non-B. Further investigations of the interferon system in patients with virus hepatitis might help to improve our understanding of the different forms of the disease. The data presently available, however, do not permit as yet to define the value of interferon in the treatment of severe forms of acute virus hepatitis.
Keywords
Hepatitis A/immunology, Hepatitis B/immunology, Hepatitis C/immunology, Hepatitis, Alcoholic/immunology, Hepatitis, Viral, Human/immunology, Humans, Interferons/blood, Kinetics
Pubmed
Web of science
Create date
28/01/2008 11:36
Last modification date
20/08/2019 13:12
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