Almost routine prophylactic cholecystectomy during laparoscopic gastric bypass is safe

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Serval ID
serval:BIB_2D0EA262C387
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Almost routine prophylactic cholecystectomy during laparoscopic gastric bypass is safe
Journal
Obesity Surgery
Author(s)
Nougou  A, Suter  M
ISSN
0960-8923
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
18
Number
5
Pages
535-539
Language
english
Abstract
Background Morbidly obese patients are at high risk to develop gallstones, and rapid weight loss after bariatric surgery further enhances this risk. The concept of prophylactic cholecystectomy during gastric bypass has been challenged recently because the risk may be lower than reported earlier and because cholecystectomy during laparoscopic gastric bypass may be more difficult and risky.
<p>Methods A review of prospectively collected data on 772 patients who underwent laparoscopic primary gastric bypass between January 2000 and August 2007 was performed. The charts of patients operated before 2004 were retrospectively reviewed regarding preoperative echography and histopathological findings.</p>
<p>Results Fifty-eight (7.5%) patients had had previous cholecystectomy. In the remaining patients, echography showed gallstones or sludge in 81 (11.3%). Cholecystectomy was performed at the time of gastric bypass in 665 patients (91.7%). Gallstones were found intraoperatively in 25 patients (3.9%), for a total prevalence of gallstones of 21.2%. The age of patients with gallstones was higher than that of gallstone-free patients (43.5 vs 38.7 years, p < 0.0001). Of the removed specimens, 81.8% showed abnormal histologic findings, mainly chronic cholecystitis and cholesterolosis. Cholecystectomy was associated with no procedure-related complication, prolonged duration of surgery by a mean of 19 min (4-45), and had no effect on the duration of hospital stay. Cholecystectomy was deemed too risky in 59 patients (8.3%) who were prescribed a 6-month course of ursodeoxycolic acid.</p>
<p>Conclusion Concomitant cholecystectomy can be performed safely in most patients during laparoscopic gastric bypass and does not prolong hospital stay. As such, it is an acceptable form of prophylaxis against stones forming during rapid weight loss. Whether it is superior to chemical prophylaxis remains to be demonstrated in a large prospective randomized study.</p>
Keywords
morbid obesity, gastric bypass, cholecystectomy, gallstones, Rapid Weight-Loss, Morbidly Obese Patients, Gallstone Formation, Ursodeoxycholic Acid, Gallbladder-Disease, Bariatric Surgery, Nonobese Patients, Prevention, Reduction, Operation
Web of science
Open Access
Yes
Create date
13/10/2009 14:07
Last modification date
01/10/2019 6:17
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