Predictors of remission from PTSD symptoms after sexual and non-sexual trauma in the community: A mediated survival-analytic approach.

Details

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State: Public
Version: Author's accepted manuscript
Serval ID
serval:BIB_2C6F1668BF6A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Predictors of remission from PTSD symptoms after sexual and non-sexual trauma in the community: A mediated survival-analytic approach.
Journal
Psychiatry research
Author(s)
Müller M., Ajdacic-Gross V., Rodgers S., Kleim B., Seifritz E., Vetter S., Egger S.T., Rössler W., Castelao E., Preisig M., Vandeleur C.
ISSN
1872-7123 (Electronic)
ISSN-L
0165-1781
Publication state
Published
Issued date
02/2018
Peer-reviewed
Oui
Volume
260
Pages
262-271
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Epidemiological data on the chronicity of posttraumatic stress disorder (PTSD) symptoms in relation to trauma type and underlying pathways are rare. The current study explored how PTSD symptoms change over time across different trauma types and examined mediators of their persistence. A trauma-exposed community sample, whereof approximately one quarter met diagnostic criteria for PTSD, provided retrospective data on the duration of PTSD symptoms. Those who remitted and those who had not at the time of assessment were compared regarding worst trauma, symptom severity, comorbidity, demographic and treatment-seeking variables. Time to remission was estimated using Cox proportional hazard models including candidate predictors of remission. A mediated survival analysis was used to explore indirect pathways that explain trauma-specific differences in remission times. Both the full sample and PTSD subgroup were analyzed separately. Overall, lower socio-economic status, lifetime and childhood sexual trauma, symptom severity, comorbid depression and past treatment were associated with non- and longer remissions. PTSD avoidance symptoms and comorbid depression were found to mediate longer remission times after lifetime or childhood sexual trauma. Our findings provide insight into the mechanisms and complicating factors of remission from PTSD symptoms after trauma, which might have important implications for therapeutic interventions.
Keywords
Adult, Aged, Cohort Studies, Comorbidity, Depression/epidemiology, Depression/rehabilitation, Depressive Disorder/epidemiology, Depressive Disorder/rehabilitation, Female, Humans, Male, Middle Aged, Psychological Trauma/epidemiology, Psychological Trauma/rehabilitation, Retrospective Studies, Sex Offenses/statistics & numerical data, Stress Disorders, Post-Traumatic/epidemiology, Stress Disorders, Post-Traumatic/rehabilitation, Survival Analysis, Switzerland/epidemiology, Avoidance, Comorbid depression, Hazard ratio, Mediated survival analysis, PTSD symptoms, Remission, Sexual and non-sexual trauma
Pubmed
Web of science
Open Access
Yes
Create date
14/12/2017 14:50
Last modification date
20/08/2019 13:11
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