Circulating ionized and total magnesium in end-stage kidney disease

Details

Serval ID
serval:BIB_2A05BCCD5E69
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Circulating ionized and total magnesium in end-stage kidney disease
Journal
Nephron
Author(s)
Pedrozzi  N. E., Truttmann  A. C., Faraone  R., Descoeudres  C. E., Wermuth  B., Luthy  C. M., Nuoffer  J. M., Frey  F. J., Bianchetti  M. G.
ISSN
0028-2766 (Print)
Publication state
Published
Issued date
1998
Volume
79
Number
3
Pages
288-92
Notes
Journal Article
Abstract
BACKGROUND: Circulating magnesium exists in the ionized state and in the undissociated form, either bound to albumin, or complexed to various anions. Until recently, only the measurement of total plasma magnesium has been possible. Now circulating ionized magnesium can be assessed as well. METHODS: Total and ionized plasma magnesium were determined in 43 patients on maintenance hemodialysis (dialysate composition: calcium 1.75 mmol/l, magnesium 0.75 mmol/l) before a dialysis session and in a group of 23 healthy subjects. RESULTS: The total (1.16 [1.03-1.31] versus 0.81 [0.78-0.89] mmol/l; median and interquartile range) and the ionized (0.71 [0.66-0.78] versus 0.54 [0.53-0.59] mmol/l) plasma magnesium levels were significantly higher (p < 0.01) and the ionized plasma magnesium fraction lower (0.61 [0.58-0.65] versus 0.67 [0.64-0.70]; p < 0.02) in patients than in controls. CONCLUSION: The determination of circulating ionized magnesium using selective electrodes is an attractive method to evaluate extracellular magnesium in kidney disease.
Keywords
Adolescent Adult Aged Aged, 80 and over Calcium/blood Child Female Humans Ions Kidney Failure, Chronic/*blood/*therapy Magnesium/*blood Male Middle Aged *Renal Dialysis
Pubmed
Web of science
Create date
28/01/2008 13:50
Last modification date
20/08/2019 13:09
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