The role of B cells in COVID-19 infection and vaccination.

Details

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State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_29D06720D861
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
The role of B cells in COVID-19 infection and vaccination.
Journal
Frontiers in immunology
Author(s)
Chen S., Guan F., Candotti F., Benlagha K., Camara NOS, Herrada A.A., James L.K., Lei J., Miller H., Kubo M., Ning Q., Liu C.
ISSN
1664-3224 (Electronic)
ISSN-L
1664-3224
Publication state
Published
Issued date
2022
Peer-reviewed
Oui
Volume
13
Pages
988536
Language
english
Notes
Publication types: Journal Article ; Review ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Abstract
B cells secrete antibodies and mediate the humoral immune response, making them extremely important in protective immunity against SARS-CoV-2, which caused the coronavirus disease 2019 (COVID-19) pandemic. In this review, we summarize the positive function and pathological response of B cells in SARS-CoV-2 infection and re-infection. Then, we structure the immunity responses that B cells mediated in peripheral tissues. Furthermore, we discuss the role of B cells during vaccination including the effectiveness of antibodies and memory B cells, viral evolution mechanisms, and future vaccine development. This review might help medical workers and researchers to have a better understanding of the interaction between B cells and SARS-CoV-2 and broaden their vision for future investigations.
Keywords
COVID-19/prevention & control, Humans, Lymphocyte Count, SARS-CoV-2, Vaccination, Viral Vaccines, B cells, COVID-19, antibody, memory B cells, vaccination
Pubmed
Web of science
Open Access
Yes
Create date
27/09/2022 12:24
Last modification date
23/01/2024 7:22
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