The role of B cells in COVID-19 infection and vaccination.
Details
Serval ID
serval:BIB_29D06720D861
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
The role of B cells in COVID-19 infection and vaccination.
Journal
Frontiers in immunology
ISSN
1664-3224 (Electronic)
ISSN-L
1664-3224
Publication state
Published
Issued date
2022
Peer-reviewed
Oui
Volume
13
Pages
988536
Language
english
Notes
Publication types: Journal Article ; Review ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Publication Status: epublish
Abstract
B cells secrete antibodies and mediate the humoral immune response, making them extremely important in protective immunity against SARS-CoV-2, which caused the coronavirus disease 2019 (COVID-19) pandemic. In this review, we summarize the positive function and pathological response of B cells in SARS-CoV-2 infection and re-infection. Then, we structure the immunity responses that B cells mediated in peripheral tissues. Furthermore, we discuss the role of B cells during vaccination including the effectiveness of antibodies and memory B cells, viral evolution mechanisms, and future vaccine development. This review might help medical workers and researchers to have a better understanding of the interaction between B cells and SARS-CoV-2 and broaden their vision for future investigations.
Keywords
COVID-19/prevention & control, Humans, Lymphocyte Count, SARS-CoV-2, Vaccination, Viral Vaccines, B cells, COVID-19, antibody, memory B cells, vaccination
Pubmed
Web of science
Open Access
Yes
Create date
27/09/2022 12:24
Last modification date
23/01/2024 7:22