Renal handling of cadmium: a study by tubular microinjections

Details

Serval ID
serval:BIB_292074C495D5
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Renal handling of cadmium: a study by tubular microinjections
Journal
Archives of Toxicology. Supplement
Author(s)
Bosco  E., Porta  N., Diezi  J.
ISSN
0171-9750
Publication state
Published
Issued date
1984
Volume
7
Pages
371-3
Notes
Journal Article
Abstract
109Cadmium was microinjected, in different chemical forms, into the proximal or distal cortical tubules of adult rats and recovery in the pelvic urine from the ipsilateral kidney was measured. There was marked uptake of inorganic cadmium along the proximal tubules, and only negligible uptake in the distal nephron. The fractional uptake of the complex cadmium-cysteine in the proximal tubule was inversely related to the cysteine concentration. The chelate cadmium-pentetic acid was completely recovered in the pelvic urine.
Keywords
Animals Cadmium/*metabolism/toxicity Kidney/drug effects/*metabolism Kidney Tubules/metabolism Male Microinjections Rats Rats, Inbred Strains
Pubmed
Create date
21/01/2008 11:54
Last modification date
20/08/2019 13:08
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