The nature and frequency of neovascular age-related macular degeneration.

Details

Serval ID
serval:BIB_2856C5DEF036
Type
Article: article from journal or magazin.
Collection
Publications
Title
The nature and frequency of neovascular age-related macular degeneration.
Journal
European journal of ophthalmology
Author(s)
Iranmanesh R., Eandi C.M., Peiretti E., Klais C.M., Garuti S., Goldberg D.E., Slakter J.S., Yannuzzi L.A.
ISSN
1120-6721 (Print)
ISSN-L
1120-6721
Publication state
Published
Issued date
2007
Peer-reviewed
Oui
Volume
17
Number
1
Pages
75-83
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
This study was designed to evaluate the frequency and nature of neovascularization in age-related macular degeneration (ARMD) utilizing the combination of digital imaging techniques, fluorescein angiography (FA), indocyanine green (ICG) angiography, and optical coherence tomography (OCT).
A complete clinical examination was performed on 100 eyes of 93 consecutive newly diagnosed patients with neovascular ARMD. Digital fluorescein angiography, ICG angiography, and OCT were also used in evaluating those patients. Comparison of the imaging techniques to determine their value in studying the nature of the lesions.
On the basis of existing fluorescein standards, 15 eyes were diagnosed with classic choroidal neovascularization (CNV), 15 with minimally classic CNV, and 70 with occult CNV. ICG angiography was superior for detecting the active vascular component in polypoidal CNV (16 eyes) and retinal angiomatous proliferation (14 eyes). OCT was more sensitive than FA for determining the presence of cystoid macular edema evident in the vast majority of eyes with retinal angiomatous proliferation (RAP).
These results suggest that FA, ICG angiography, and OCT, when used in combination, will assist clinicians in best determining the precise nature of the neovascular process in ARMD.
Keywords
Aged, Aged, 80 and over, Choroid/blood supply, Choroidal Neovascularization/diagnosis, Choroidal Neovascularization/etiology, Coloring Agents, Female, Fluorescein Angiography/methods, Humans, Indocyanine Green, Macular Degeneration/complications, Macular Degeneration/diagnosis, Male, Middle Aged, Prospective Studies, Retinal Neovascularization/diagnosis, Retinal Neovascularization/etiology, Retinal Vessels/pathology, Tomography, Optical Coherence/methods
Pubmed
Web of science
Create date
12/03/2021 10:08
Last modification date
26/03/2021 7:35
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