Alcohol-cue exposure decreases response inhibition towards alcohol-related stimuli in detoxified alcohol-dependent patients
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Serval ID
serval:BIB_281382ED6E33
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Alcohol-cue exposure decreases response inhibition towards alcohol-related stimuli in detoxified alcohol-dependent patients
Journal
Psychiatry Research
ISSN
0165-1781
Publication state
Published
Issued date
2017
Peer-reviewed
Oui
Volume
249
Pages
232-239
Language
english
Abstract
The induction of alcohol craving and the cognitive processing of alcohol-related stimuli in alcohol-dependent
patients have been reported to compete with inhibitory control and contribute to alcohol relapse. The aim of the
present study is to investigate whether the induction of a craving state, using an alcohol cue exposure paradigm,
influences response inhibition towards both neutral stimuli and alcohol-related stimuli in alcohol-dependent
patients. Thirty-one detoxified alcohol-dependent patients were exposed to either their preferred alcoholic
beverage or to a glass of water. They then performed a modified stop signal task, which used alcohol-related
words, neutral words and non-words, and a lexical decision as the Go response. The alcohol-cue exposure group
reported significantly higher alcohol craving and showed higher percentages of commission errors towards
alcohol-related words than the control group. All participants, but especially those of the alcohol-cue exposure
group, showed also shorter reaction times when alcohol words were used as targets in go trials. The induction of
alcohol craving in detoxified alcohol-dependent patients increases the motivational salience value of alcohol
stimuli, leading them to automatically approach alcohol-related cues and therefore impairing response
inhibition towards those stimuli.
patients have been reported to compete with inhibitory control and contribute to alcohol relapse. The aim of the
present study is to investigate whether the induction of a craving state, using an alcohol cue exposure paradigm,
influences response inhibition towards both neutral stimuli and alcohol-related stimuli in alcohol-dependent
patients. Thirty-one detoxified alcohol-dependent patients were exposed to either their preferred alcoholic
beverage or to a glass of water. They then performed a modified stop signal task, which used alcohol-related
words, neutral words and non-words, and a lexical decision as the Go response. The alcohol-cue exposure group
reported significantly higher alcohol craving and showed higher percentages of commission errors towards
alcohol-related words than the control group. All participants, but especially those of the alcohol-cue exposure
group, showed also shorter reaction times when alcohol words were used as targets in go trials. The induction of
alcohol craving in detoxified alcohol-dependent patients increases the motivational salience value of alcohol
stimuli, leading them to automatically approach alcohol-related cues and therefore impairing response
inhibition towards those stimuli.
Keywords
Alcohol Use Disorder, Alcohol, Craving, Inhibition
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Create date
10/01/2020 9:30
Last modification date
15/01/2020 17:04