A pooled analysis of case-control studies of thyroid cancer: cigarette smoking and consumption of alcohol, coffee, and tea

Details

Serval ID
serval:BIB_2807EAC3603F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
A pooled analysis of case-control studies of thyroid cancer: cigarette smoking and consumption of alcohol, coffee, and tea
Journal
Cancer Causes and Control
Author(s)
Mack Wendy J., Preston-Martin Susan, Dal Maso Luigino, Galanti Rosaria, Xiang Min, Franceschi Silvia, Hallquist Arne, Jin Fan, Kolonel Laurence, La Vecchia Carlo, Levi Fabio, Linos Athena, Lund Eiliv, McTiernan Anne, Mabuchi Kiyohiko, Negri Eva, Wingren Gun, Ron Elaine
ISSN
0957-5243
Publication state
Published
Issued date
2003
Volume
14
Number
8
Pages
773-785
Notes
Réf.: R 03/119 SAPHIRID:44923
Abstract
[Abstract] OBJECTIVE: To analyze the role of smoking, alcohol, coffee and tea in relation to thyroid cancer, we conducted a pooled analysis of 14 case-control studies conducted in the United States, Europe, and Asia. METHODS: The sample consisted of 2725 thyroid cancer cases (2247 females, 478 males) and 4776 controls (3699 females, 1077 males). Conditional logistic regression with stratification on study, age at diagnosis, and gender was used to compute odds ratios and 95% confidence intervals. RESULTS: Thyroid cancer risk was reduced in persons who had ever smoked. The relationship was more pronounced in current smokers (OR = 0.6, 95% CI = 0.6-0.7) than former smokers (OR = 0.9, 95% CI = 0.8-1.1). There were significant trends of reduced risk with greater duration and frequency of smoking. For consumption of wine and beer, there was a significant trend of decreasing thyroid cancer risk (p = 0.02) that was not maintained after adjustment for current smoking (p = 0.12). Thyroid cancer risk was not associated with consumption of coffee or tea. These findings were consistent in both gender-specific and histology-specific (papillary and follicular) analyses. CONCLUSIONS: Pooled analyses of these geographically diverse case-control data indicate a reduced thyroid cancer risk associated with current smoking. A reduced risk associated with alcohol was eliminated after adjustment for smoking, and caffeinated beverages did not alter thyroid cancer risk. [Authors]
Keywords
Alcohol Drinking , Coffee , Smoking , Tea , Thyroid Neoplasms
Pubmed
Web of science
Create date
06/03/2008 15:31
Last modification date
20/08/2019 13:07
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