Energy, macronutrients and laryngeal cancer risk

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It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_26D8787AF96A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Energy, macronutrients and laryngeal cancer risk
Journal
Annals of Oncology
Author(s)
Bosetti Cristina, La Vecchia Carlo, Talamini Renato, Negri Eva, Levi Fabio, Fryzek J., McLaughlin J.K., Garavello Werner, Franceschi Silvia
ISSN
0923-7534
Publication state
Published
Issued date
2003
Peer-reviewed
Oui
Volume
14
Number
6
Pages
907-912
Language
english
Notes
Réf. IUMSP: R 03/49
SAPHIRID:44883
Abstract
BACKGROUND: A role for diet in laryngeal carcinogenesis has been suggested, but only a few studies have examined the potential relationship with a wide variety of macronutrients. PATIENTS AND METHODS: A case-control study was conducted between 1992 and 2000 in Italy and Switzerland, including 527 incident cases of laryngeal cancer, and 1297 controls hospitalized for acute, non-neoplastic conditions. The subjects' usual diet was investigated through a validated food frequency questionnaire, including 78 foods and beverages. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using unconditional multiple logistic regression models. RESULTS: Cases reported higher energy intake than controls. The continuous OR for 100 kcal/day was 1.16 (95% CI 1.12-1.21) for alcohol energy, and 1.02 (95% CI 1.01-1.04) for non-alcohol energy. A significantly increased risk of laryngeal cancer was observed for animal protein (continuous OR = 1.21, 95% CI 1.03-1.41), polyunsaturated fats other than linoleic and linolenic fatty acids (OR = 1.43, 95% CI 1.19-1.70), and cholesterol intake (OR = 1.43, 95% CI 1.19-1.71). Laryngeal cancer risk was slightly reduced with increasing vegetable protein (OR = 0.75, 95% CI 0.62-0.91), sugar (OR = 0.84, 95% CI 0.71-1.00) and monounsaturated fatty acid intake (OR = 0.83, 95% CI 0.70-0.99). CONCLUSIONS: Laryngeal cancer cases have a higher energy intake than control subjects, and report a higher intake of animal protein and cholesterol. [authors]
Pubmed
Web of science
Open Access
Yes
Create date
06/03/2008 15:31
Last modification date
25/09/2019 6:08
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