Social inequalities in sleep-disordered breathing: Evidence from the CoLaus|HypnoLaus study.

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State: Public
Version: Author's accepted manuscript
License: Not specified
Serval ID
serval:BIB_26CACF23F71F
Type
Article: article from journal or magazin.
Collection
Publications
Title
Social inequalities in sleep-disordered breathing: Evidence from the CoLaus|HypnoLaus study.
Journal
Journal of sleep research
Author(s)
Petrovic D., Haba-Rubio J., Carmeli C., Vollenweider P., Heinzer R., Stringhini S.
ISSN
1365-2869 (Electronic)
ISSN-L
0962-1105
Publication state
Published
Issued date
10/2019
Peer-reviewed
Oui
Volume
28
Number
5
Pages
e12799
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Sleep-disordered breathing is a common condition, related to a higher cardiometabolic and neurocognitive risk. The main risk factors for sleep-disordered breathing include obesity, craniofacial characteristics, male sex and age. However, some studies have suggested that adverse socioeconomic circumstances and lifestyle-related behaviours such as smoking and alcohol use, may also be risk factors for sleep-disordered breathing. Here, we investigate the associations between socioeconomic status and sleep-disordered breathing, as measured by sleep apnea-hypopnea and oxygen desaturation indexes. Furthermore, we assess whether these associations are explained by lifestyle-related factors (smoking, sedentary behaviour, alcohol use and body mass index [BMI]). We used data from the CoLaus|HypnoLaus study, a population-based study including 2162 participants from Lausanne (Switzerland). Socioeconomic status was measured through occupation and education. Sleep-disordered breathing was assessed through polysomnography and measured using the apnea-hypopnea index (AHI: number of apnea/hypopnea events/hr: ≥15/≥30 events), and the ≥3% oxygen desaturation index (ODI: number of oxygen desaturation events/hr: ≥15/≥30 events). Lower occupation and education were associated with higher AHI and ODI (occupation: AHI30, odds ratio (OR) = 1.88, 95% confidence interval (CI) [1.07; 3.31]; ODI30, OR = 2.29, 95% CI [1.19; 4.39]; education: AHI30, OR = 1.21, 95% CI [0.85; 1.72]; ODI30, OR = 1.26, 95% CI [0.83; 1.91]). BMI was associated with socioeconomic status and AHI/ODI, and contributed to the socioeconomic gradient in SDB, with mediation estimates ranging between 43% and 78%. In this Swiss population-based study, we found that low socioeconomic status is a risk factor for sleep-disordered breathing, and that these associations are partly explained by BMI. These findings provide a better understanding of the mechanisms underlying social differences in sleep-disordered breathing and may help implement policies for identifying high-risk profiles for this disorder.
Keywords
BMI, mediation, obstructive sleep apnea, oxygen desaturation, sleep-disordered breathing, socioeconomic status, BMI
Pubmed
Web of science
Create date
04/12/2018 16:29
Last modification date
24/09/2019 6:11
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