Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC-EORP EUROASPIRE V survey in 27 countries.
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Serval ID
serval:BIB_26AE265CC332
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC-EORP EUROASPIRE V survey in 27 countries.
Journal
Atherosclerosis
Working group(s)
EUROASPIRE V collaborators, Writing Committee, Scientific Steering/ Executive Committee, Coordinating centre, Diabetes centre, Data management centre, Statistical analysis centre, Central laboratory, Study centres, organisations, investigators and other research personnel (National Co-ordinators in each country are indicated by asterisk
Contributor(s)
De Backer G., Jankowski P., Kotseva K., Mirrakhimov E., Reiner Z., Rydén L., Tokgözoğlu L., Wood D., De Bacquer D., Kotseva K., De Backer G., Abreu A., Aguiar C., Badariene J., Bruthans J., Castro Conde A., Cifkova R., Crowley J., Davletov K., Bacquer D., De Smedt D., De Sutter J., Deckers J.W., Dilic M., Dolzhenko M., Druais H., Dzerve V., Erglis A., Fras Z., Gaita D., Gotcheva N., Grobbee D.E., Gyberg V., Hasan Ali H., Heuschmann P., Hoes A.W., Jankowski P., Lalic N., Lehto S., Lovic D., Maggioni A.P., Mancas S., Marques-Vidal P., Mellbin L., Miličić D., Mirrakhimov E., Oganov R., Pogosova N., Reiner Ž., Rydén L., Stagmo M., Störk S., Sundvall J., Tokgözoğlu L., Tsioufis K., Vulic D., Wood D., Wood D.A., Kotseva K., Jennings C., Adamska A., Adamska S., Rydén L., Mellbin L., Tuomilehto J., Schnell O., Druais H., Fiorucci E., Glemot M., Larras F., Missiamenou V., Maggioni A., Taylor C., Ferreira T., Lemaitre K., Bacquer D., De Backer G., Raman L., Sundvall J., DeSmedt D., De Sutter J., Willems A.M., De Pauw M., Vervaet P., Bollen J., Dekimpe E., Mommen N., Van Genechten G., Dendale P., Bouvier C.A., Chenu P., Huyberechts D., Persu A., Dilic M., Begic A., Durak Nalbantic A., Dzubur A., Hadzibegic N., Iglica A., Kapidjic S., Osmanagic Bico A., Resic N., Sabanovic Bajramovic N., Zvizdic F., Vulic D., Kovacevic-Preradovic T., Popovic-Pejicic S., Djekic D., Gnjatic T., Knezevic T., Kovacevic-Preradovic T., Kos L., Popovic-Pejicic S., Stanetic B., Topic G., Gotcheva N., Georgiev B., Terziev A., Vladimirov G., Angelov A., Kanazirev B., Nikolaeva S., Tonkova D., Vetkova M., Milicic D., Reiner Ž., Bosnic A., Dubravcic M., Glavina M., Mance M., Pavasovic S., Samardzic J., Batinic T., Crljenko K., Delic-Brkljacic D., Dula K., Golubic K., Klobucar I., Kordic K., Kos N., Nedic M., Olujic D., Sedinic V., Blazevic T., Pasalic A., Percic M., Sikic J., Bruthans J., Cífková R., Hašplová K., Šulc P., Wohlfahrt P., Mayer O., Cvíčela M., Filipovský J., Gelžinský J., Hronová M., Hasan-Ali H., Bakery S., Mosad E., Hamed H.B., Ibrahim A., Elsharef M.A., Kholef E.F., Shehata A., Youssef M., Elhefny E., Farid H., Moustafa T.M., Sobieh M.S., Kabil H., Abdelmordy A., Lehto S., Kiljander E., Kiljander P., Koukkunen H., Mustonen J., Cremer C., Frantz S., Haupt A., Hofmann U., Ludwig K., Melnyk H., Noutsias M., Karmann W., Prondzinsky R., Herdeg C., Hövelborn T., Daaboul A., Geisler T., Keller T., Sauerbrunn D., Walz-Ayed M., Ertl G., Leyh R., Störk S., Heuschmann P., Ehlert T., Klocke B., Krapp J., Ludwig T., Käs J., Starke C., Ungethüm K., Wagner M., Wiedmann S., Tsioufis K., Tolis P., Vogiatzi G., Sanidas E., Tsakalis K., Kanakakis J., Koutsoukis A., Vasileiadis K., Zarifis J., Karvounis C., Crowley J., Gibson I., Houlihan A., Kelly C., O'Donnell M., Bennati M., Cosmi F., Mariottoni B., Morganti M., Cherubini A., Di Lenarda A., Radini D., Ramani F., Francese M.G., Gulizia M.M., Pericone D., Davletov K., Aigerim K., Zholdin B., Amirov B., Assembekov B., Chernokurova E., Ibragimova F., Kodasbayev A., Markova A., Mirrakhimov E., Asanbaev A., Toktomamatov U., Tursunbaev M., Zakirov U., Abilova S., Arapova R., Bektasheva E., Esenbekova J., Neronova K., Asanbaev A., Baigaziev K., Toktomamatov U., Zakirov U., Baitova G., Zheenbekov T., Erglis A., Andrejeva T., Bajare I., Kucika G., Labuce A., Putane L., Stabulniece M., Dzerve V., Klavins E., Sime I., Badariene J., Gedvilaite L., Pečiuraite D., Sileikienė V., Skiauteryte E., Solovjova S., Sidabraite R., Briedis K., Ceponiene I., Jurenas M., Kersulis J., Martinkute G., Vaitiekiene A., Vasiljevaite K., Veisaite R., Plisienė J., Šiurkaitė V., Vaičiulis Ž., Jankowski P., Czarnecka D., Kozieł P., Podolec P., Nessler J., Gomuła P., Mirek-Bryniarska E., Bogacki P., Wiśniewski A., Pająk A., Wolfshaut-Wolak R., Bućko J., Kamiński K., Łapińska M., Paniczko M., Raczkowski A., Sawicka E., Stachurska Z., Szpakowicz M., Musiał W., Dobrzycki S., Bychowski J., Kosior D.A., Krzykwa A., Setny M., Kosior D.A., Rak A., Gąsior Z., Haberka M., Gąsior Z., Haberka M., Szostak-Janiak K., Finik M., Liszka J., Botelho A., Cachulo M., Sousa J., Pais A., Aguiar C., Durazzo A., Matos D., Gouveia R., Rodrigues G., Strong C., Guerreiro R., Aguiar J., Abreu A., Cruz M., Daniel P., Morais L., Moreira R., Rosa S., Rodrigues I., Selas M., Gaita D., Mancas S., Apostu A., Cosor O., Gaita L., Giurgiu L., Hudrea C., Maximov D., Moldovan B., Mosteoru S., Pleava R., Ionescu M., Parepa I., Pogosova N., Arutyunov A., Ausheva A., Isakova S., Karpova A., Salbieva A., Sokolova O., Vasilevsky A., Pozdnyakov Y., Antropova O., Borisova L., Osipova I., Lovic D., Aleksic M., Crnokrak B., Djokic J., Hinic S., Vukasin T., Zdravkovic M., Lalic N.M., Jotic A., Lalic K., Lukic L., Milicic T., Macesic M., Stanarcic Gajovic J., Stoiljkovic M., Djordjevic D., Kostic S., Tasic I., Vukovic A., Fras Z., Jug B., Juhant A., Krt A., Kugonjič U., Chipayo Gonzales D., Gómez Barrado J.J., Kounka Z., Marcos Gómez G., Mogollón Jiménez M.V., Ortiz Cortés C., Perez Espejo P., Porras Ramos Y., Colman R., Delgado J., Otero E., Pérez A., Fernández-Olmo M.R., Torres-LLergo J., Vasco C., Barreñada E., Botas J., Campuzano R., González Y., Rodrigo M., de Pablo C., Velasco E., Hernández S., Lozano C., González P., Castro A., Dalmau R., Hernández D., Irazusta F.J., Vélez A., Vindel C., Gómez-Doblas J.J., García Ruíz V., Gómez L., Gómez García M., Jiménez-Navarro M., Molina Ramos A., Marzal D., Martínez G., Lavado R., Vidal A., Rydén L., Boström-Nilsson V., Kjellström B., Shahim B., Smetana S., Hansen O., Stensgaard-Nake E., Deckers J.W., Klijn A.J., Mangus TJP, Peters RJG, Scholte Op Reimer W., Snaterse M., Aydoğdu S., Erol C., Otürk S., Tulunay Kaya C., Ahmetoğlu Y., Ergene O., Akdeniz B., Çırgamış D., Akkoyun H Kültürsay S., Kayıkçıoğlu M., Çatakoğlu A.B., Çengel A., Koçak A.A., Ağırbaşlı M.A., Açıksarı G., Çekin M.E., Tokgözoğlu L., Kaya E.B., Koçyiğit D., Öngen Z., Özmen E., Sansoy V., Kaya A., Oktay V., Temizhan A., Ünal S., Yakut I., Kalkan A.K., Bozkurt E., Kasapkara H.A., Dolzhenko M., Faradzh C., Hrubyak L., Konoplianyk L., Kozhuharyova N., Lobach L., Nesukai V., Nudchenko O., Simagina T., Yakovenko L., Azarenko V., Potabashny V., Bazylevych A., Bazylevych M., Kaminska K., Panchenko L., Shershnyova O., Ovrakh T., Serik S., Kolesnik T., Kosova H., Wood D., Adamska A., Adamska S., Jennings C., Kotseva K., Hoye P Atkin A., Fellowes D., Lindsay S., Atkinson C., Kranilla C., Vinod M., Beerachee Y., Bennett C., Broome M., Bwalya A., Caygill L., Dinning L., Gillespie A., Goodfellow R., Guy J., Idress T., Mills C., Morgan C., Oustance N., Singh N., Yare M., Jagoda J.M., Bowyer H., Christenssen V., Groves A., Jan A., Riaz A., Gill M., Sewell T.A., Gorog D., Baker M., De Sousa P., Mazenenga T., Porter J., Haines F., Peachey T., Taaffe J., Wells K., Ripley D.P., Forward H., McKie H., Pick S.L., Thomas H.E., Batin P.D., Exley D., Rank T., Wright J., Kardos A., Sutherland S.B., Wren L., Leeson P., Barker D., Moreby B., Sawyer J., Stirrup J., Brunton M., Brodison A., Craig J., Peters S., Kaprielian R., Bucaj A., Mahay K., Oblak M., Gale C., Pye M., McGill Y., Redfearn H., Fearnley M.
ISSN
1879-1484 (Electronic)
ISSN-L
0021-9150
Publication state
Published
Issued date
06/2019
Peer-reviewed
Oui
Volume
285
Pages
135-146
Language
english
Notes
Publication types: Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
One of the objectives of the ESC-EORP EUROASPIRE V survey is to determine how well European guidelines on the management of dyslipidaemias are implemented in coronary patients.
Standardized methods were used by trained technicians to collect information on 7824 patients from 130 centers in 27 countries, from the medical records and at a visit at least 6 months after hospitalization for a coronary event. All lipid measurements were performed in one central laboratory. Patients were divided into three groups: on high-intensity LDL-C-lowering-drug therapy (LLT), on low or moderate-intensity LLT and on no LLT.
At the time of the visit, almost half of the patients were on a high-intensity LLT. Between hospital discharge and the visit, LLT had been reduced in intensity or interrupted in 20.8% of the patients and had been started or increased in intensity in 11.7%. In those who had interrupted LLT or had reduced the intensity, intolerance to LLT and the advice of their physician were reported as the reason why in 15.8 and 36.8% of the cases, respectively. LDL-C control was better in those on a high-intensity LLT compared to those on low or moderate intensity LLT. LDL-C control was better in men than women and in patients with self-reported diabetes.
The results of the EUROASPIRE V survey show that most coronary patients have a less than optimal management of LDL-C. More professional strategies are needed, aiming at lifestyle changes and LLT adapted to the need of the individual patient.
Standardized methods were used by trained technicians to collect information on 7824 patients from 130 centers in 27 countries, from the medical records and at a visit at least 6 months after hospitalization for a coronary event. All lipid measurements were performed in one central laboratory. Patients were divided into three groups: on high-intensity LDL-C-lowering-drug therapy (LLT), on low or moderate-intensity LLT and on no LLT.
At the time of the visit, almost half of the patients were on a high-intensity LLT. Between hospital discharge and the visit, LLT had been reduced in intensity or interrupted in 20.8% of the patients and had been started or increased in intensity in 11.7%. In those who had interrupted LLT or had reduced the intensity, intolerance to LLT and the advice of their physician were reported as the reason why in 15.8 and 36.8% of the cases, respectively. LDL-C control was better in those on a high-intensity LLT compared to those on low or moderate intensity LLT. LDL-C control was better in men than women and in patients with self-reported diabetes.
The results of the EUROASPIRE V survey show that most coronary patients have a less than optimal management of LDL-C. More professional strategies are needed, aiming at lifestyle changes and LLT adapted to the need of the individual patient.
Keywords
Aged, Anticholesteremic Agents/therapeutic use, Cholesterol, LDL/blood, Coronary Disease/blood, Coronary Disease/complications, Dyslipidemias/blood, Dyslipidemias/complications, Dyslipidemias/drug therapy, Europe, Female, Guideline Adherence/statistics & numerical data, Health Care Surveys, Humans, Male, Middle Aged, Coronary heart disease, Dyslipidaemia, EUROASPIRE, LDL-Cholesterol, Lipid lowering therapy, Secondary prevention
Pubmed
Web of science
Create date
23/05/2024 14:11
Last modification date
01/06/2024 6:18
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