Réirradiation des tumeurs de la tête et du cou : volumes cibles, évolutions techniques et perspectives [Re-irradiation of head and neck cancers: Target volumes, technical evolutions and prospects]
Details
Serval ID
serval:BIB_26A3F5D023DE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Réirradiation des tumeurs de la tête et du cou : volumes cibles, évolutions techniques et perspectives [Re-irradiation of head and neck cancers: Target volumes, technical evolutions and prospects]
Journal
Cancer radiotherapie
ISSN
1769-6658 (Electronic)
ISSN-L
1278-3218
Publication state
Published
Issued date
04/2018
Peer-reviewed
Oui
Volume
22
Number
2
Pages
171-179
Language
french
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
Malignant tumors of the head and neck have a predominantly regional recurrence pattern, with most deaths resulting from this progression. Optimization of re-radiation in recurrence setting is a major objective for these patients. Extensive research has been carried out with the PubMed search engine to find publications dealing with this topic. The first attempts to reirradiate the ORL sphere date back to the 1980s and the first to be performed by intensity modulation conformational radiotherapy (IMRT) date back to the late 1990s. Compared to 3 dimensional conformal radiotherapy, IMRT improves clinical outcomes and reduces toxicity. In IMRT series, associated or not with concomitant chemotherapy, the locoregional control obtained at 2 years was of the order of 45 to 65% and the overall survival of 15 to 60%, depending on predictive factors. Grade 3 acute toxicity occurred on the order of 10 to 30% and late-grade 3 toxicity on the order of 15 to 50%. In a selected population with low volumes tumors, stereotactic re-irradiation at a minimum dose of 35Gy obtained outcome comparable to IMRT. Re-irradiation of head and neck tumors by proton therapy is rare. The toxicity rate appears to be lower than that usually seen after photon therapy. However, we do not have a long follow-up. This technique therefore remains reserved for search protocols and represents a future perspective in these situations.
Keywords
Head and Neck Neoplasms/radiotherapy, Humans, Neoplasm Recurrence, Local/radiotherapy, Radiosurgery/adverse effects, Radiosurgery/methods, Radiotherapy Dosage, Radiotherapy, Conformal/adverse effects, Radiotherapy, Conformal/methods, Radiotherapy, Intensity-Modulated/adverse effects, Radiotherapy, Intensity-Modulated/methods, Retreatment, Cancer ORL, Head and neck cancer, Radiation therapy, Radiothérapie, Re-irradiation, Recurrence, Revue, Récidive cancer de la tête et cou, Réirradiation
Pubmed
Web of science
Publisher's website
Create date
23/08/2021 11:38
Last modification date
24/09/2024 12:09