Mycobacterial genome structure

Details

Serval ID
serval:BIB_2696499CA0D4
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Mycobacterial genome structure
Journal
Electrophoresis
Author(s)
Philipp  W. J., Schwartz  D. C., Telenti  A., Cole  S. T.
ISSN
0173-0835 (Print)
Publication state
Published
Issued date
04/1998
Volume
19
Number
4
Pages
573-6
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Apr
Abstract
Genome maps have been constructed for the mycobacterial pathogens Mycobacterium leprae and Mycobacterium tuberculosis, as well as for the attenuated vaccine strain Mycobacterium bovis BCG Pasteur. While the chromosomes of M. tuberculosis and M. bovis BCG Pasteur show extensive conservation at the gross level, comparison with M. leprae revealed a high degree of diversification, with a mosaic-like pattern apparent. The ordered libraries of M. tuberculosis and M. leprae produced during the course of these studies played a central role in the genome sequencing projects of these two bacilli, showing the utility of this approach for systematic sequencing of bacterial genomes.
Keywords
Chromosome Mapping Chromosomes, Bacterial *Genome, Bacterial Mycobacterium/*genetics
Pubmed
Web of science
Create date
25/01/2008 14:45
Last modification date
20/08/2019 13:05
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