Lymphomatoid granulomatosis in a renal transplant patient.

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Serval ID
serval:BIB_2535E8D4AD49
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Lymphomatoid granulomatosis in a renal transplant patient.
Journal
Pediatric Nephrology
Author(s)
Cachat F., Meagher-Villemure K., Guignard J.P.
ISSN
0931-041X (Print)
ISSN-L
0931-041X
Publication state
Published
Issued date
2003
Volume
18
Number
8
Pages
838-842
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Abstract
Lymphomatoid granulomatosis is a rare angiocentric and angiodestructive pulmonary angiitis considered as a variant of the lymphoproliferative disorder group. Patients with organ transplantation are at an increased risk for post-transplant lymphoproliferative disorders secondary to their immunosuppression. However, lymphomatoid granulomatosis has rarely been described in patients with renal transplantation. It often presents with severe pulmonary signs. We describe a case whose initial presentation was an isolated VIth nerve palsy. We review the radiological and pathological findings and discuss the etiopathogenesis and therapeutic options of this particular lymphoproliferative disorder. With careful and stepwise reduction in her immunosuppression, our patient showed a complete disappearance of her lymphomatoid granulomatosis, and she is clinically well more than 3 years after the diagnosis, with good kidney function.
Keywords
Adolescent, Female, Graft Rejection/drug therapy, Humans, Immunosuppressive Agents/adverse effects, Kidney Transplantation, Lymphomatoid Granulomatosis/chemically induced, Lymphomatoid Granulomatosis/pathology, Magnetic Resonance Imaging, Tomography, X-Ray Computed
Pubmed
Web of science
Open Access
Yes
Create date
29/01/2008 18:35
Last modification date
01/10/2019 6:17
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