Drug monographs on drugs which are frequently analysed in the context of Therapeutic Drug Monitoring = Arzneimittel-Monographien für Medikamente, die regelmässig im Rahmen des Therapeutic Drug Monitorings analysiert werden

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Serval ID
serval:BIB_2534A7E3A40F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Drug monographs on drugs which are frequently analysed in the context of Therapeutic Drug Monitoring = Arzneimittel-Monographien für Medikamente, die regelmässig im Rahmen des Therapeutic Drug Monitorings analysiert werden
Journal
LaboratoriumsMedizin = Journal of Laboratory Medicine
Author(s)
Rentsch Katharina, Baumann Pierre, Fathi Marc, Grignaschi Nathalie, Magnin Jean-Luc, Thormann Wolfgang, Todesco Liliane, Wenk Markus, Werner Dominique
ISSN
0342-3026
Publication state
Published
Issued date
2006
Peer-reviewed
Oui
Volume
30
Number
6
Pages
443-452
Language
english
Notes
SAPHIRID:62469
Abstract
In addition to the monographs which were published last year by the working group "Drug Monitoring" of the Swiss Society of Clinical Chemistry (SSCC) [1], new monographs have been written. The aim of these monographs is to give an overview of the most important information necessary for ordering a drug analysis or interpreting the results. Therefore, the targeted readers comprise laboratory health professionals and all receivers of laboratory reports. There is information provided on the indication for therapeutic drug monitoring, protein binding, metabolic pathways and enzymes involved, elimination half-life and elimination routes, and on therapeutic or toxic concentrations. Preanalytical considerations are of particular importance for therapeutic drug monitoring. Therefore, information is provided regarding a reasonable timing for the determination of drug concentrations as well as steady-state concentrations after changing the dose. Furthermore, the stability of the drug and its metabolite(s) after blood sampling is described. For readers with a specific interest in drug analysis, references to important publications are given. The number of monographs will be continuously enlarged. The updated files are presented on the homepage of the SSCC (www.sscc.ch).
Open Access
Yes
Create date
25/02/2009 15:12
Last modification date
01/10/2019 6:17
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