Colite à Clostridium difficile: nouvelles recommandations de prise en charge [Clostridium difficile infections: update on new European recommendations].

Details

Serval ID
serval:BIB_253172DF06C4
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Colite à Clostridium difficile: nouvelles recommandations de prise en charge [Clostridium difficile infections: update on new European recommendations].
Journal
Revue Médicale Suisse
Author(s)
Tissot F., Maillard M.H.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
2014
Volume
10
Number
427
Pages
913-6, 918-9
Language
french
Notes
Publication types: English Abstract ; Journal Article Publication Status: ppublish
Abstract
Clostridium difficile infections: update on new European recommandations While metronidazole and vancomycin have been the only drug options to date for the treatment of C. difficile infection, new therapeutic approaches with promising results have recently emerged for the treatment of the first episode and relapses. Fidaxomicin is a new macrocyclic antibiotic more active against C. difficile and with a narrow spectrum allowing preservation of the intestinal microbiota. While having the same efficacy as vancomycin for the treatment of the first episode, this agent is associated with a lower rate of relapse. The highest relapse-free cure rate is achieved through fecal microbiota transplantation, which should be considered for patients with multiple relapses.
Keywords
Anti-Bacterial Agents/therapeutic use, Clostridium difficile, Enterocolitis, Pseudomembranous/therapy, Feces/microbiology, Humans, Practice Guidelines as Topic, Transplantation
Pubmed
Create date
06/03/2015 12:12
Last modification date
20/08/2019 13:03
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