"Dark-blood" dual-energy computed tomography angiography for thoracic aortic wall imaging.

Details

Serval ID
serval:BIB_2349B3162843
Type
Article: article from journal or magazin.
Collection
Publications
Title
"Dark-blood" dual-energy computed tomography angiography for thoracic aortic wall imaging.
Journal
European radiology
Author(s)
Rotzinger D.C., Si-Mohamed S.A., Shapira N., Douek P.C., Meuli R.A., Boussel L.
ISSN
1432-1084 (Electronic)
ISSN-L
0938-7994
Publication state
Published
Issued date
22/07/2019
Peer-reviewed
Oui
Language
english
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Abstract
To assess the capability of a newly developed material decomposition method from contrast-enhanced dual-energy CT images, aiming to better visualize the aortic wall and aortic intramural hematoma (IMH), compared with true non-contrast (TNC) CT.
Twenty-two patients (11 women; mean age, 61 ± 20 years) with acute chest pain underwent 25 dual-layer non-contrast and contrast-enhanced CT. CT-angiography images were retrospectively processed using two-material decomposition analysis, where we defined the first material as the content of a region of interest placed in the ascending aorta for each patient, and the second material as water. Two independent radiologists assessed the images from the second material termed "dark-blood" images and the TNC images regarding contrast-to-noise ratio (CNR) between the wall and the lumen, diagnostic quality regarding the presence of aortic wall thickening, and the inner/outer vessel wall conspicuity.
Diagnostic quality scores in normal aortic segments were 0.9 ± 0.3 and 2.7 ± 0.6 (p < 0.001) and wall conspicuity scores were 0.7 ± 0.5 and 1.8 ± 0.3 (p < 0.001) on TNC and dark-blood images, respectively. In aortic segments with IMH, diagnostic quality scores were 1.7 ± 0.5 and 2.4 ± 0.6 (p < 0.001) and wall conspicuity scores were 0.7 ± 0.7 and 1.8 ± 0.3 (p < 0.001) on TNC and dark-blood images, respectively. In normal aortic segments, CNRs were 0.3 ± 0.2 and 2.8 ± 0.9 on TNC and dark-blood images, respectively (p < 0.001). In aortic segments with IMH, CNRs were 0.3 ± 0.2 and 4.0 ± 1.0 on TNC and dark-blood images, respectively (p < 0.001).
Compared with true non-contrast CT, dark-blood material decomposition maps enhance quantitative and qualitative image quality for the assessment of normal aortic wall and IMH.
• Current dual-energy CT-angiography provides virtual non-contrast and bright-blood images. • Dark-blood images represent a new way to assess the vascular wall structure with dual-energy CT and can improve the lumen-to-wall contrast compared with true non-contrast CT. • This dual-energy CT material decomposition method is likely to improve contrast resolution in other applications as well, taking advantage of the high spatial resolution of CT.
Keywords
Aorta, Computed tomography angiography, Hematoma, Technology assessment, Thorax
Pubmed
Create date
01/08/2019 13:43
Last modification date
21/08/2019 6:33
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