Thalidomide: un vieux medicament aux nouvelles indications. [Thalidomide: new indications for an old drug]

Details

Serval ID
serval:BIB_22DA9249B5FA
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Thalidomide: un vieux medicament aux nouvelles indications. [Thalidomide: new indications for an old drug]
Journal
Revue Médicale Suisse
Author(s)
Laffitte  E.
ISSN
1660-9379 (Print)
Publication state
Published
Issued date
04/2005
Volume
1
Number
16
Pages
1074, 1077-80
Notes
English Abstract
Journal Article
Review --- Old month value: Apr 20
Abstract
Thalidomide has several mechanisms of action: a hypnosedative effect, several immuno-modulatory properties and an anti-angiogenic action. Thalidomide has been used in several cutaneous inflammatory disorders (such as erythema nodosum leprosum in lepromatous leprosy, cutaneous lupus erythematosus, severe aphtosis), cancers (relapsed/refractory multiple myeloma) and inflammatory conditions. Several side effects are associated with thalidomide: teratogenicity, peripheral neuropathy and deep venous thrombosis; some are minor, such as somnolence or abdominal pain and endocrinologic disturbances. Use of thalidomide is strictly controlled with close adherence to a birth control program and close monitoring for early development of peripheral neuropathy.
Keywords
Humans Skin Diseases/drug therapy Thalidomide/*therapeutic use
Pubmed
Create date
25/01/2008 16:42
Last modification date
20/08/2019 13:00
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