Two Birds with One Stone: Skull Base Meningioma and Jugulotympanic Paragangliomas with Somatostatin Receptor Positron Emission Tomography.

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Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_22BBF405A36F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Two Birds with One Stone: Skull Base Meningioma and Jugulotympanic Paragangliomas with Somatostatin Receptor Positron Emission Tomography.
Journal
Diagnostics
Author(s)
Treglia G., Raditchkova M., Giovanella L., Stelmes J.J., Bosetti D.G., Martucci F.
ISSN
2075-4418 (Print)
ISSN-L
2075-4418
Publication state
Published
Issued date
13/09/2021
Peer-reviewed
Oui
Volume
11
Number
9
Pages
1669
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
We describe the case of a 74-year-old female patient previously treated with radiation therapy for a meningioma of the skull base and with surgery for a right tympanic paraganglioma. After the morphological progression of the meningioma demonstrated by magnetic resonance imaging (MRI), the patient underwent somatostatin receptor positron emission tomography/computed tomography (SR-PET/CT) with Gallium-68 DOTATATE for restaging. This examination showed increased somatostatin receptor expression by the meningioma and confirmed its extension as already assessed by MRI (endocranial extension, skull base involvement and invasion of the right orbit). Furthermore, SR-PET/CT detected two small right jugulotympanic pararagangliomas with high somatostatin receptor expression. Lastly, SR-PET/CT demonstrated that this patient would be an ideal candidate for peptide receptor radionuclide therapy (PRRT) that can be used for the treatment of progressive/treatment-refractory meningiomas and relapsed paragangliomas with high somatostatin receptors expression, both conditions coexisting in this case.
Keywords
DOTATATE, MRI, PET, gallium-68, magnetic resonance imaging, meningioma, paraganglioma, positron emission tomography, skull base, somatostatin
Pubmed
Web of science
Open Access
Yes
Create date
04/10/2021 10:07
Last modification date
23/11/2022 7:08
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