Fonction ventilatoire et reactivite bronchique des recrues. [Ventilatory function and bronchial responsiveness in army recruits]

Details

Serval ID
serval:BIB_22ABC34CD653
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Fonction ventilatoire et reactivite bronchique des recrues. [Ventilatory function and bronchial responsiveness in army recruits]
Journal
Schweizerische Medizinische Wochenschrift
Author(s)
Zellweger  J. P., Fitting  J. W.
ISSN
0036-7672 (Print)
Publication state
Published
Issued date
10/1990
Volume
120
Number
40
Pages
1466-72
Notes
English Abstract
Journal Article --- Old month value: Oct 6
Abstract
Lung function and determination of the bronchial responsiveness to methacholine were performed in two groups of Swiss army recruits aged 20 years (total 233), where 144 had respiratory complaints or a history of prior asthma and 89 were asymptomatic, among whom 26 had recently suffered from upper respiratory tract infection (URTI). A bronchial obstruction (ratio FEV1/FVC less than 73%) was observed among 6% of the subjects with symptoms, 6% of the asymptomatic control subjects and 4% in the group with recent URTI. The differences are not significant. A bronchial hyperresponsiveness (defined as PD20 less than 900 mcg) was observed in 45% of the symptomatic subjects (54% in 109 recruits complaining of dyspnea on exertion) against 3% in the control group (p less than 0.001) and 12% in the group with recent URTI (NS, p = 0.14). Among subjects complaining of dyspnea on exertion, more than half have an obvious bronchial hyperresponsiveness at a level usually observed in asthmatics, most of them without any clinical finding or permanent bronchial obstruction. Although the sensitivity of the determination of bronchial responsiveness is low (47%) its specificity is high (97%). The test allows detection of some subjects with asthma among young subjects complaining of respiratory troubles in spite of normal clinical examination and lung function. A normal level of bronchial responsiveness practically excludes asthma.
Keywords
Adult Asthma, Exercise-Induced/physiopathology *Bronchial Provocation Tests Bronchoconstriction Exertion/physiology Humans *Lung Volume Measurements Male *Military Personnel
Pubmed
Web of science
Create date
25/01/2008 9:43
Last modification date
20/08/2019 13:00
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