Dynamic asymmetry of the vestibulo-ocular reflex in unilateral peripheral vestibular and cochleovestibular loss

Details

Serval ID
serval:BIB_22A16A6D04C7
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Dynamic asymmetry of the vestibulo-ocular reflex in unilateral peripheral vestibular and cochleovestibular loss
Journal
Laryngoscope
Author(s)
Maire  R., van Melle  G.
ISSN
0023-852X (Print)
Publication state
Published
Issued date
02/2000
Volume
110
Number
2 Pt 1
Pages
256-63
Notes
Journal Article --- Old month value: Feb
Abstract
OBJECTIVE: Rotatory tests in the horizontal plane have shown various degrees of vestibulo-ocular reflex (VOR) asymmetry in patients after surgical deafferentation of one labyrinth. The purpose of this work was to characterize dynamic horizontal VOR responses among patients presenting with a unilateral peripheral labyrinthine deficit of nonsurgical origin and to compare results in isolated vestibular loss versus cochleovestibular loss. STUDY DESIGN: This study included 40 patients who presented with an acute, spontaneous unilateral peripheral labyrinthine lesion. Twenty-two patients had vestibular loss alone (without associated hearing impairment) and 18 presented with a cochleovestibular deficit (sudden hearing loss with vertigo). The majority of these patients were part of a long-term protocol to evaluate vestibular compensation. METHODS: All patients underwent both the clockwise test and the counterclockwise rotatory test in the horizontal plane, using brief impulses of moderate intensity. Results were analyzed by a simplified model of vestibular function, allowing a parametric estimation of the response. RESULTS: A weak and transitory horizontal VOR asymmetry was observed in the 22 patients with vestibular loss. However, the 18 patients with cochleovestibular loss demonstrated a more severe and persistent asymmetry. CONCLUSIONS: This study revealed a difference in the dynamic characteristics of the horizontal VOR between patients with vestibular loss and those with cochleovestibular loss. Our results support the presence of an extensive labyrinthine lesion in cochleovestibular deficit that involves the otolith organs. The implications of this involvement on the central mechanisms of otolith-canal interaction are discussed.
Keywords
Adult Aged Aged, 80 and over Cochlear Diseases/*physiopathology Electronystagmography Female Humans Male Middle Aged Otolithic Membrane Reflex, Vestibulo-Ocular/*physiology Rotation Vestibular Diseases/*physiopathology
Pubmed
Web of science
Open Access
Yes
Create date
25/01/2008 11:00
Last modification date
20/08/2019 13:00
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