Retrieval practice improves memory in patients with schizophrenia: new perspectives for cognitive remediation.

Details

Serval ID
serval:BIB_2208CC7E2978
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Retrieval practice improves memory in patients with schizophrenia: new perspectives for cognitive remediation.
Journal
BMC psychiatry
Author(s)
Jantzi C., Mengin A.C., Serfaty D., Bacon E., Elowe J., Severac F., Meyer N., Berna F., Vidailhet P.
ISSN
1471-244X (Electronic)
ISSN-L
1471-244X
Publication state
Published
Issued date
11/11/2019
Peer-reviewed
Oui
Volume
19
Number
1
Pages
355
Language
english
Notes
Publication types: Controlled Clinical Trial ; Journal Article
Publication Status: epublish
Abstract
Schizophrenia is associated with severe cognitive deficits, particularly episodic memory deficits, that interfere with patients' socio-professional functioning. Retrieval practice (also known as testing effect) is a well-established episodic memory strategy that involves taking an initial memory test on a previously learned material. Testing later produces robust long-term memory improvements in comparison to the restudy of the same material both in healthy subjects and in some clinical populations with memory deficits. While retrieval practice might represent a relevant cognitive remediation strategy in patients with schizophrenia, studies using optimal procedures to explore the benefits of retrieval practice in this population are still lacking. Therefore, the purpose of our study was to investigate the benefits of retrieval practice in patients with schizophrenia.
Nineteen stabilised outpatients with schizophrenia (DSM-5 criteria) and 20 healthy controls first studied a list of 60 word-pairs (30 pairs with weak semantic association and 30 non associated pairs). Half the pairs were studied again (restudy condition), while only the first word of the pair was presented and the subject had to recall the second word for the other half (retrieval practice condition). The final memory test consisted in a cued-recall which took place 2 days later. Statistical analyses were performed using Bayesian methods.
Cognitive performances were globally altered in patients. However, in both groups, memory performances for word-pairs were significantly better after retrieval practice than after restudy (56.1% vs 35.7%, respectively, Pr(RP > RS) > 0.999), and when a weak semantic association was present (64.7% vs 27.1%, respectively; Pr(weak > no) > 0.999). Moreover, the positive effect of RP was observed in all patients but one.
Our study is the first to demonstrate that retrieval practice efficiently improves episodic memory in comparison to restudy in patients with schizophrenia. This learning strategy should therefore be considered as a useful tool for cognitive remediation programs. In this perspective, future studies might explore retrieval practice using more ecological material.
Keywords
Adult, Bayes Theorem, Cognitive Remediation/methods, Cues, Female, Humans, Male, Memory Disorders/therapy, Memory, Episodic, Mental Recall, Schizophrenia/complications, Schizophrenia/therapy, Verbal Learning, Young Adult, Schizophrenia, cognitive remediation, memory, retrieval practice, testing effect
Pubmed
Web of science
Open Access
Yes
Create date
13/01/2021 20:38
Last modification date
14/01/2021 6:26
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