Suivi du syndrome métabolique induit par les antipsychotiques atypiques: recommandations et perspectives pharmacogénétiques [Follow-up of the metabolic syndrome induced by atypical antipsychotics: recommendations and pharmacogenetics perspectives]

Details

Serval ID
serval:BIB_2191648F6C07
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Suivi du syndrome métabolique induit par les antipsychotiques atypiques: recommandations et perspectives pharmacogénétiques [Follow-up of the metabolic syndrome induced by atypical antipsychotics: recommendations and pharmacogenetics perspectives]
Journal
Revue medicale suisse
Author(s)
Choong E., Solida A., Lechaire C., Conus P., Eap C.B.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
17/09/2008
Peer-reviewed
Oui
Volume
4
Number
171
Pages
1994-1996,1998-1999
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
Despite a better overall tolerance as compared to classical antipsychotics, atypical antipsychotics are not devoid of side-effects, notably metabolic factors (weight gain, alteration of lipid and glucose profile). These side-effects are very troubling concerning long term morbidity and mortality and may also influence compliance towards drugs. The department of psychiatry of the Hospital University Centre has established a guideline on the clinical monitoring of patients receiving atypical antipsychotics, based on recently published consensus, which will be presented here. In addition, recent studies show that weight gain and metabolic alterations induced by this type of medication may be influenced by the genetic background of the patients. Such studies should allow, in the near future, to adapt the treatment for each patient.

Keywords
Antidepressive Agents, Second-Generation/adverse effects, Glucose Intolerance/chemically induced, Humans, Leptin/genetics, Metabolic Syndrome X/chemically induced, Metabolic Syndrome X/genetics, Pharmacogenetics, Receptors, Leptin/genetics, Weight Gain/drug effects
Pubmed
Create date
17/10/2008 14:26
Last modification date
09/10/2020 20:21
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