Prediction of bone strength of distal forearm using radius bone mineral density and phalangeal speed of sound.

Details

Serval ID
serval:BIB_21355000F017
Type
Article: article from journal or magazin.
Collection
Publications
Title
Prediction of bone strength of distal forearm using radius bone mineral density and phalangeal speed of sound.
Journal
Bone
Author(s)
Wu C., Hans D., He Y., Fan B., Njeh C.F., Augat P., Richards J., Genant H.K.
ISSN
8756-3282
Publication state
Published
Issued date
2000
Peer-reviewed
Oui
Volume
26
Number
5
Pages
529-533
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Abstract
This investigation compares quantitative ultrasound (QUS) measurement of the phalanges with peripheral quantitative computed tomography (pQCT) and dual X-ray absorptiometry (DXA) measurement of the forearm, to estimate the strength of the distal radius in 13 cadaveric forearms. The cadavers were scanned at the distal radius by pQCT and DXA for bone mineral density (BMD) and at the approximate phalanges by QUS for speed of sound (SOS). The distal radii were subjected to a simulated Colles fracture produced with a materials testing machine. The load at which the distal radius was fractured was considered as a representation of bone strength. The bone strength correlated significantly with SOS at different phalanges (r = 0.63-0.72), BMD at different regions of interest by DXA (r = 0.67-0.75), and cortical BMD at different sites by pQCT (r = 0.61-0.67). Standard stepwise regression analysis showed that adding phalangeal SOS into forearm densitometric variables significantly enhanced the statistical power for prediction of the strength of the distal radius. Our results suggest that, for assessment of site-specific distal forearm strength, QUS measurement of the phalanges is comparable to forearm densitometry. Phalangeal QUS may add clinical value if distal forearm strength has a high priority.
Keywords
Aged, Aged, 80 and over, Biomechanics, Fingers, Fractures, Bone, Humans, Middle Aged, Radius, Tomography, X-Ray Computed
Pubmed
Web of science
Create date
02/03/2009 12:33
Last modification date
20/08/2019 12:57
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