Extracorporeal oxygen and CO2 transfer of a polypropylene dimpled membrane lung with variable secondary flows: partial bypass in the dog

Details

Serval ID
serval:BIB_2121FEF5F162
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Extracorporeal oxygen and CO2 transfer of a polypropylene dimpled membrane lung with variable secondary flows: partial bypass in the dog
Journal
Journal of Biomedical Engineering
Author(s)
Dorrington  K. L., Gardaz  J. P., Bellhouse  B. J., Sykes  M. K.
ISSN
0141-5425 (Print)
Publication state
Published
Issued date
01/1986
Volume
8
Number
1
Pages
36-42
Notes
Comparative Study
In Vitro
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jan
Abstract
In vivo gas transfer performance, during veno-venous bypass, is presented for one form of the Oxford membrane lung in which vortex mixing is induced in blood flow across a dimpled polypropylene membrane. Good agreement has been found with in vitro data presented in an earlier paper. Two experiments were extended to attain total extracorporeal CO2 removal with apnoeic diffusion oxygenation to motionless lungs. Measurements of arterial oxygen partial pressure during apnoea suggest that the time-constant for equilibration of alveolar nitrogen partial pressure with that on the gas side of the membrane lung is of the order of 100 min.
Keywords
Animals Artificial Organs *Blood Flow Velocity Carbon Dioxide/*metabolism Cardiopulmonary Bypass/methods Dogs *Extracorporeal Circulation *Membranes, Artificial Models, Biological Oxygen/*metabolism Partial Pressure Plastics/*therapeutic use Polypropylenes/*therapeutic use Respiration, Artificial/*methods
Pubmed
Web of science
Create date
28/01/2008 10:48
Last modification date
20/08/2019 12:57
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