Fatigue after stroke: a major but neglected issue.

Details

Serval ID
serval:BIB_21103
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Fatigue after stroke: a major but neglected issue.
Journal
Cerebrovascular Diseases
Author(s)
Staub F., Bogousslavsky J.
ISSN
1015-9770
Publication state
Published
Issued date
2001
Volume
12
Number
2
Pages
75-81
Language
english
Notes
Publication types: Journal Article ; Review
Abstract
Subjective fatigue, defined as a feeling of early exhaustion developing during mental activity, with weariness, lack of energy and aversion to effort, remains virtually unstudied in patients with stroke, bur recent surveys suggest that it is a major, commonly overlooked, stroke sequela. While the few existing series did not show significant correlations between fatigue and stroke severity, lesion location, cognitive and neurological impairment and depression, recent neurobehavioral studies have highlighted an association between fatigue and brainstem and thalamic lesions. This suggests that fatigue may be linked to the interruption of neural networks involved in tonic attention, such as the reticular activating system. In fact, several subtypes of fatigue may develop after stroke, in connection with cognitive sequelae, neurological impairment, psychological factors and sleep disorders. A challenge is to identify and delineate these different subtypes and to distinguish them from mood disorders, which frequently coexist. We emphasize the concept of 'primary' poststroke fatigue, which may develop in the absence of depression or a significant cognitive sequela, and which may be linked to attentional deficits resulting from specific damage to the reticular formation and related structures involved in the subcortical attentional network. In the patients with excellent neurological and neuropsychological recovery, poststroke fatigue may be the only persisting sequela, which may severely limit their return to previous activities. The recognition of poststroke fatigue may be critical during recovery and rehabilitation after stroke.
Keywords
Fatigue/etiology, Fatigue/physiopathology, Humans, Stroke/complications, Stroke/physiopathology
Pubmed
Web of science
Create date
19/11/2007 12:16
Last modification date
20/08/2019 12:57
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