Isolated limb perfusion: the European experience.

Details

Serval ID
serval:BIB_21082
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Isolated limb perfusion: the European experience.
Journal
Surgical Oncology Clinics of North America
Author(s)
Lejeune F.J., Kroon B.B., Di Filippo F., Hoekstra H.J., Santinami M., Liénard D., Eggermont A.M.
ISSN
1055-3207 (Print)
ISSN-L
1055-3207
Publication state
Published
Issued date
2001
Peer-reviewed
Oui
Volume
10
Number
4
Pages
821-32, ix
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Isolated limb perfusion (ILP) is a method of cancer treatment allowing the administration of high doses of anticancer agents in a limb surgically isolated from systemic circulation. By using continuous leakage monitoring and using the drug melphalan, a high complete remission rate is obtained in patients with melanoma. In patients with sarcomas, ILP with tumor necrosis factor and melphalan represents a neoadjuvant treatment for limb-sparing surgery. This treatment is the first demonstration of an active anti-angiogenic regimen in the clinic.
Keywords
Antineoplastic Agents/administration & dosage, Chemotherapy, Cancer, Regional Perfusion, Europe, Humans, Interferon-gamma/administration & dosage, Melanoma/drug therapy, Melanoma/secondary, Sarcoma/drug therapy, Soft Tissue Neoplasms/drug therapy, Tumor Necrosis Factor-alpha/administration & dosage
Pubmed
Create date
19/11/2007 12:16
Last modification date
20/08/2019 12:57
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