Dietary supplementation with carotenoids improves immunity without increasing its cost in a crustacean.

Details

Serval ID
serval:BIB_1F62B05C8357
Type
Article: article from journal or magazin.
Collection
Publications
Title
Dietary supplementation with carotenoids improves immunity without increasing its cost in a crustacean.
Journal
American Naturalist
Author(s)
Babin A., Biard C., Moret Y.
ISSN
1537-5323 (Electronic)
ISSN-L
0003-0147
Publication state
Published
Issued date
2010
Peer-reviewed
Oui
Volume
176
Number
2
Pages
234-241
Language
english
Abstract
Costs of immunity include self-harming autoreactivity through the production of cytotoxic chemicals. While carotenoids stimulate immunity and reduce oxidative stress during immune activity in vertebrates, their involvement in invertebrate immunity is unclear. Recently, a positive correlation between immune defenses and concentration of carotenoids in the hemolymph was demonstrated in the crustacean Gammarus pulex, suggesting an important role of carotenoids in invertebrate immunity. We tested the causality of this relationship by using a dietary supplementation with carotenoids and measuring several immune parameters. We found that dietary carotenoids had a broad immunostimulating effect, enhancing phenoloxidase activity and resistance to a bacterial infection. When immune challenged, gammarids fed with carotenoids did not pay an additional survival cost because of autoreactivity, despite their intensified immune activity. Therefore, dietary carotenoids improved gammarids' immunity without inducing additional self-harming. This underlines the importance of carotenoids in both the regulation and the evolution of immunity in G. pulex.
Keywords
Adjuvants, Immunologic/pharmacology, Amphipoda/drug effects, Amphipoda/immunology, Animals, Carotenoids/pharmacology, Immunity, Innate/drug effects
Pubmed
Web of science
Create date
27/02/2012 10:56
Last modification date
20/08/2019 12:55
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