International consensus on laryngeal preservation strategies in laryngeal and hypopharyngeal cancer.
Details
Serval ID
serval:BIB_1F0BF53E82C5
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
International consensus on laryngeal preservation strategies in laryngeal and hypopharyngeal cancer.
Journal
The Lancet. Oncology
Working group(s)
Consensus Group for Laryngeal Preservation
Contributor(s)
Agarwal J.P., Ansarin M., Argiris A., Balermpas P., Battisti NML, Bellini E., Bertolin A., Carobbio ALC, Chiesa-Estomba C.M., Cirauqui B., Crosetti E., De Oliveira T.B., Deganello A., Dietz A., Eriksen J.G., Eskander A., Fakhry N., Falco A., Farina D., Ferrarotto R., Franzese C., Ghosh Laskar S., Golusiński W., Hanna E.Y., Irish J.C., Kiyota N., Kowalski L.P., Krishnan S., Lee N., Leemans C.R., Licitra L., Locati L.D., Machiels J.P., Marchi F., Mattavelli D., Mehanna H., Mercante G., Montalto N., Morbini P., O'Sullivan B., Oliva M., Orlandi E., Paderno A., Paleri V., Pameijer F., Perri F., Persio R., Piazza C., Pointreau Y., Presutti L., Ravanelli M., Rischin D., Rodrigo J.P., Ruaro A., Sanguineti G., Simon C., Siu L., Spreafico A., Spriano G., Taboni S., Tassini U., Tribius S., Van den Brekel M., Vander Poorten V., Viros Porcuna D.
ISSN
1474-5488 (Electronic)
ISSN-L
1470-2045
Publication state
Published
Issued date
05/2025
Peer-reviewed
Oui
Volume
26
Number
5
Pages
e264-e281
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
This Policy Review summarises an expert Delphi consensus process on larynx-preservation treatments in patients affected by intermediate-to-advanced laryngeal or hypopharyngeal squamous cell carcinoma. The experts, who represented all perspectives involved in multidisciplinary management of these patients and included patient representatives, approved 137 consensus statements that cover several relevant areas in the field of larynx-preserving treatments. Statements are grouped in the following topics: granular indications for T2-T3 cancer, indications for T4a cancer, indications for salvage organ-preservation surgery after chemoradiation failure, laryngeal function at baseline, which comorbidities are contraindications and to what extent, organ preservation in older patients: selection criteria, post-treatment surveillance, prognostic and predictive factors, listening to the patient's preferences: tools and implementation, prehabilitation and rehabilitation protocols, and cost-effectiveness of different laryngeal preservation approaches. We present a high-level summary of the results of the consensus process, with detailed reference to the full list of statements and supporting literature.
Keywords
Humans, Hypopharyngeal Neoplasms/pathology, Hypopharyngeal Neoplasms/therapy, Hypopharyngeal Neoplasms/surgery, Consensus, Organ Sparing Treatments/methods, Organ Sparing Treatments/adverse effects, Laryngeal Neoplasms/pathology, Laryngeal Neoplasms/therapy, Laryngeal Neoplasms/surgery, Larynx/pathology, Larynx/surgery, Delphi Technique, Squamous Cell Carcinoma of Head and Neck/pathology, Salvage Therapy
Pubmed
Create date
09/05/2025 15:51
Last modification date
10/05/2025 7:11