Diet-induced thermogenesis in chronic obstructive pulmonary disease.

Details

Serval ID
serval:BIB_1E915CFC56E1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Diet-induced thermogenesis in chronic obstructive pulmonary disease.
Journal
The American review of respiratory disease
Author(s)
Hugli O., Frascarolo P., Schutz Y., Jéquier E., Leuenberger P., Fitting J.W.
ISSN
1073-449X
0003-0805
Publication state
Published
Issued date
1993
Volume
148
Number
6 Pt 1
Pages
1479-83
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
Abstract
Increased resting energy expenditure and malnutrition are frequently observed in patients with COPD. The aim of this study was to examine the possible contribution of an increased diet-induced thermogenesis (DIT) to weight loss. Eleven patients with COPD in stable clinical state and 11 healthy control subjects were studied. Resting energy expenditure (REE) was measured by standard methods of indirect calorimetry, using a ventilated canopy. Premeal REE was measured after an overnight fast. All subjects then received a balanced liquid test meal with a caloric content that was 0.3 times their REE extrapolated to 24 h. Diet-induced thermogenesis was measured over 130 min. Premeal REE was 109.9 +/- 11.7% of predicted values in the COPD group and 97.5 +/- 9.6% of predicted in the control group (p < 0.01). Seventy minutes after the test meal, REE had increased by 18.8 +/- 8.5% in the COPD group and by 15.1 +/- 5.8% in the control group (NS). After 130 min, REE had increased by 16.4 +/- 7.1% in the COPD group and by 12.4 +/- 5.3% in the control group (NS). The DIT expressed as a percentage of the caloric content of the meal was 4.3 +/- 1.6% in the COPD group and 3.3 +/- 1.4% in the control group (NS). We conclude that patients with stable COPD, although hypermetabolic at rest, do not show an increased DIT.
Keywords
Basal Metabolism, Calorimetry, Indirect, Eating, Energy Metabolism, Humans, Lung Diseases, Obstructive, Male, Middle Aged, Nutritional Status, Respiratory Mechanics, Thyroid Function Tests, Weight Loss
Pubmed
Web of science
Create date
29/01/2008 8:41
Last modification date
20/08/2019 12:54
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