The Museo Egizio holds 18 Amduat papyri originated from Thebes between the mid of the Twenty-first and the mid of the Twenty-second Dynasty. In the two centuries since they were brought to the museum, they have left only sporadic traces in Egyptological literature. They were recently the subject of the author’s MA thesis and are presently that of his PhD project, which aims to prepare the first edition of these documents. The article examines these manuscripts by applying a conceptual framework that integrates philological and semiotic analysis, providing textual and visual insight into Third Intermediate Period scribal practices and the emergence of a new funerary tradition at the end of the Twenty-first Dynasty.