Interfractional set-up errors evaluation by daily electronic portal imaging of IMRT in head and neck cancer patients.

Details

Serval ID
serval:BIB_1B809A69621E
Type
Article: article from journal or magazin.
Collection
Publications
Title
Interfractional set-up errors evaluation by daily electronic portal imaging of IMRT in head and neck cancer patients.
Journal
Acta Oncologica
Author(s)
Pehlivan B., Pichenot C., Castaing M., Auperin A., Lefkopoulos D., Arriagada R., Bourhis J.
ISSN
1651-226X (Electronic)
ISSN-L
0284-186X
Publication state
Published
Issued date
2009
Peer-reviewed
Oui
Volume
48
Number
3
Pages
440-445
Language
english
Notes
Publication types: Evaluation Studies ; Journal Article Publication Status: ppublish
Abstract
INTRODUCTION: Interfractional set-up errors were assessed from daily portal images (PI) registration for head and neck cancer patients. We aimed to evaluate whether a daily PI is worthwhile and we derived the Planning Target Volume (PTV) margins from the estimation of systematic and random errors.
MATERIAL AND METHODS: Twenty patients were treated in supine position with a fixed 5-point mask immobilisation system and head-and-knee supports. DRRs (Digitally Reconstructed Radiograph) were obtained from the planning CT-scan and considered the reference images to be compared with two orthogonal PI by matching bone anatomy landmarks. A total of 567 PI were done. For the set-up errors analysis, we determined the systematic, random, and overall standard deviations (SD), as well as the overall means in three directions (cranio caudal CC, medio lateral ML and anterior posterior AP). PTV-margins were calculated according to three methods. Differences of SD regarding the overall displacements among portals performed every day and each 2, 3, or 4 days were tested.
RESULTS: The systematic set-up errors were less than 1 mm in the three directions whereas the random set-up errors were around 2 mm. PTV margins varied from 3 to 4 mm in the 3 directions. Corrections were significant in the CC direction only, in which the set-up error increased significantly when the scenario of one PI every 3 fractions was adopted.
CONCLUSIONS: It is of practical importance to apply on-line protocols with contouring of the bony landmarks on the PI in order to decrease the systematic mean error in this patient group. This study suggested that a PI in AP and ML directions once a week and every two days in the CC direction would be adequate to overcome the problem of set-up errors.
Keywords
Adult, Aged, Aged, 80 and over, Diagnostic Imaging, Dose Fractionation, Electronics, Female, Head and Neck Neoplasms/radiotherapy, Humans, Image Processing, Computer-Assisted, Immobilization/instrumentation, Immobilization/methods, Lymph Nodes/radiation effects, Male, Middle Aged, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted/methods, Radiotherapy, Conformal, Radiotherapy, Intensity-Modulated/methods
Pubmed
Web of science
Open Access
Yes
Create date
01/12/2014 17:23
Last modification date
20/08/2019 12:52
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