The association of anxio-depressive disorders and depression with motoric cognitive risk syndrome: results from the baseline assessment of the Canadian longitudinal study on aging.
Details
Serval ID
serval:BIB_1B4344A44A93
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The association of anxio-depressive disorders and depression with motoric cognitive risk syndrome: results from the baseline assessment of the Canadian longitudinal study on aging.
Journal
GeroScience
ISSN
2509-2723 (Electronic)
ISSN-L
2509-2723
Publication state
Published
Issued date
08/2019
Peer-reviewed
Oui
Volume
41
Number
4
Pages
409-418
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
Motoric cognitive risk syndrome (MCR), anxio-depressive disorders (ADD), and depression are associated with cognitive complaint and slow gait speed. The study aims to examine (1) the association of ADD and depression with MCR, and (2) the influence of the type and the severity of ADD and age on this association in older adults. A total of 29,569 participants free from cognitive impairment with walking speed measure recruited at baseline in the Canadian Longitudinal Study on Aging (CLSA) Comprehensive were selected in this cross-sectional study. They were separated into different sub-groups based on their age groups (i.e., 45-54, 55-64, 65-74, and ≥ 75) and the presence of MCR. Anxiety, mood, and depressive disorders (ADD) were assessed. Depression was defined by the Center for Epidemiological Studies Depression Scale (CES-D) score ≥ 10. The overall prevalence of MCR was 7.0 % and was greater in the youngest age group (8.9 %) as compared to the other age groups (P < 0.05). There was a higher prevalence of ADD and depression in individuals with MCR compared to those without MCR for all age groups (P ≤ 0.001). Depression was significantly associated with MCR regardless of age group (odds ratio ≥ 3.65 with P ≤ 0.001). The association of ADD with MCR depended on the accumulation of disorders and not their type, and was weaker and more inconstant in the oldest age group as compared to younger age groups. MCR is associated with ADD and depression in both younger and older individuals. This association is stronger for depression in younger individuals.
Keywords
Aged, Anxiety/epidemiology, Canada/epidemiology, Cognitive Dysfunction/epidemiology, Cross-Sectional Studies, Depression/epidemiology, Female, Humans, Longitudinal Studies, Male, Middle Aged, Mood Disorders/epidemiology, Walking Speed, CLSA, Cognitive complaint, Depression, Epidemiology, Older adults, Walking speed
Pubmed
Web of science
Create date
03/10/2023 7:36
Last modification date
04/10/2023 5:59