Difference in performance between 3D and 4D CBCT for lung imaging: a dose and image quality analysis.

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Version: Final published version
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Serval ID
serval:BIB_19ADA467B85A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Difference in performance between 3D and 4D CBCT for lung imaging: a dose and image quality analysis.
Journal
Journal of applied clinical medical physics
Author(s)
Thengumpallil S., Smith K., Monnin P., Bourhis J., Bochud F., Moeckli R.
ISSN
1526-9914 (Electronic)
ISSN-L
1526-9914
Publication state
Published
Issued date
08/11/2016
Peer-reviewed
Oui
Volume
17
Number
6
Pages
6459
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
The study was to describe and to compare the performance of 3D and 4D CBCT imaging modalities by measuring and analyzing the delivered dose and the image quality. The 3D (Chest) and 4D (Symmetry) CBCT Elekta XVI lung IGRT protocols were analyzed. Dose profiles were measured with TLDs inside a dedicated phantom. The dosimetric indicator cone-beam dose index (CBDI) was evaluated. The image quality analysis was performed by assessing the contrast transfer function (CTF), the noise power spectrum (NPS) and the noise-equivalent quanta (NEQ). Artifacts were also evaluated by simulating irregular breathing variations. The two imaging modalities showed different dose distributions within the phantom. At the center, the 3D CBCT delivered twice the dose of the 4D CBCT. The CTF was strongly reduced by motion compared to static conditions, resulting in a CTF reduction of 85% for the 3D CBCT and 65% for the 4D CBCT. The amplitude of the NPS was two times higher for the 4D CBCT than for the 3D CBCT. In the presence of motion, the NEQ of the 4D CBCT was 50% higher than the 3D CBCT. In the presence of breathing irregularities, the 4D CBCT protocol was mainly affected by view-aliasing artifacts, which were typically cone-beam artifacts, while the 3D CBCT protocol was mainly affected by duplication artifacts. The results showed that the 4D CBCT ensures a reasonable dose and better image quality when mov-ing targets are involved compared to 3D CBCT. Therefore, 4D CBCT is a reliable imaging modality for lung free-breathing radiation therapy.
Keywords
Algorithms, Cone-Beam Computed Tomography/methods, Four-Dimensional Computed Tomography/methods, Humans, Image Processing, Computer-Assisted/methods, Image Processing, Computer-Assisted/standards, Lung Neoplasms/diagnostic imaging, Lung Neoplasms/radiotherapy, Motion, Phantoms, Imaging, Radiographic Image Interpretation, Computer-Assisted/methods, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted/methods, Radiotherapy, Image-Guided/methods, Radiotherapy, Intensity-Modulated/methods, Respiration, Signal-To-Noise Ratio
Pubmed
Create date
22/12/2016 15:29
Last modification date
05/05/2020 6:20
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