Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality.

Details

Ressource 1Download: BIB_1872B1AF27C9.P001.pdf (1828.97 [Ko])
State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_1872B1AF27C9
Type
Article: article from journal or magazin.
Publication sub-type
Minutes: analyse of a published work.
Collection
Publications
Title
Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality.
Journal
Genome Research
Author(s)
Simola D.F., Wissler L., Donahue G., Waterhouse R.M., Helmkampf M., Roux J., Nygaard S., Glastad K.M., Hagen D.E., Viljakainen L., Reese J.T., Hunt B.G., Graur D., Elhaik E., Kriventseva E.V., Wen J., Parker B.J., Cash E., Privman E., Childers C.P., Muñoz-Torres M.C., Boomsma J.J., Bornberg-Bauer E., Currie C.R., Elsik C.G., Suen G., Goodisman M.A., Keller L., Liebig J., Rawls A., Reinberg D., Smith C.D., Smith C.R., Tsutsui N., Wurm Y., Zdobnov E.M., Berger S.L., Gadau J.
ISSN
1549-5469 (Electronic)
ISSN-L
1088-9051
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Volume
23
Number
8
Pages
1235-1247
Language
english
Abstract
Genomes of eusocial insects code for dramatic examples of phenotypic plasticity and social organization. We compared the genomes of seven ants, the honeybee, and various solitary insects to examine whether eusocial lineages share distinct features of genomic organization. Each ant lineage contains ∼4000 novel genes, but only 64 of these genes are conserved among all seven ants. Many gene families have been expanded in ants, notably those involved in chemical communication (e.g., desaturases and odorant receptors). Alignment of the ant genomes revealed reduced purifying selection compared with Drosophila without significantly reduced synteny. Correspondingly, ant genomes exhibit dramatic divergence of noncoding regulatory elements; however, extant conserved regions are enriched for novel noncoding RNAs and transcription factor-binding sites. Comparison of orthologous gene promoters between eusocial and solitary species revealed significant regulatory evolution in both cis (e.g., Creb) and trans (e.g., fork head) for nearly 2000 genes, many of which exhibit phenotypic plasticity. Our results emphasize that genomic changes can occur remarkably fast in ants, because two recently diverged leaf-cutter ant species exhibit faster accumulation of species-specific genes and greater divergence in regulatory elements compared with other ants or Drosophila. Thus, while the "socio-genomes" of ants and the honeybee are broadly characterized by a pervasive pattern of divergence in gene composition and regulation, they preserve lineage-specific regulatory features linked to eusociality. We propose that changes in gene regulation played a key role in the origins of insect eusociality, whereas changes in gene composition were more relevant for lineage-specific eusocial adaptations.
Pubmed
Web of science
Open Access
Yes
Create date
25/04/2013 15:51
Last modification date
04/01/2020 7:17
Usage data