Long-term functional and quality of life outcomes after coloanal anastomosis for distal rectal cancer.
Details
State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_184E117347DC
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Long-term functional and quality of life outcomes after coloanal anastomosis for distal rectal cancer.
Journal
Diseases of the Colon and Rectum
ISSN
0012-3706 (Print)
ISSN-L
0012-3706
Publication state
Published
Issued date
2006
Peer-reviewed
Oui
Volume
49
Number
9
Pages
1266-1274
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
PURPOSE: This study was designed to evaluate the long-term functional and quality-of-life outcomes of patients after coloanal anastomosis for distal rectal cancer.
METHODS: A total of 192 patients underwent coloanal anastomosis between 1982 and 2001 at two tertiary referral institutions. Standardized and validated questionnaires to assess functional and quality-of-life outcomes were mailed to 151 patients, of which 121 patients responded (median follow-up, 65 months).
RESULTS: Patients receiving pelvic radiotherapy had more bowel function problems than patients who did not receive pelvic radiotherapy. No significant differences in relevant functional and quality-of-life outcomes were seen among patients who received preoperative or postoperative pelvic radiotherapy. Patients requiring permanent diversion as a result of complications of the surgery had decreased quality of life.
CONCLUSIONS: Coloanal anastomosis for distal rectal cancer has favorable long-term outcomes. Pelvic radiotherapy has an adverse effect on subsequent bowel function (whether given preoperatively or postoperatively) in patients who maintain intestinal continuity. Loss of intestinal continuity after a coloanal anastomosis is associated with diminished quality of life.
METHODS: A total of 192 patients underwent coloanal anastomosis between 1982 and 2001 at two tertiary referral institutions. Standardized and validated questionnaires to assess functional and quality-of-life outcomes were mailed to 151 patients, of which 121 patients responded (median follow-up, 65 months).
RESULTS: Patients receiving pelvic radiotherapy had more bowel function problems than patients who did not receive pelvic radiotherapy. No significant differences in relevant functional and quality-of-life outcomes were seen among patients who received preoperative or postoperative pelvic radiotherapy. Patients requiring permanent diversion as a result of complications of the surgery had decreased quality of life.
CONCLUSIONS: Coloanal anastomosis for distal rectal cancer has favorable long-term outcomes. Pelvic radiotherapy has an adverse effect on subsequent bowel function (whether given preoperatively or postoperatively) in patients who maintain intestinal continuity. Loss of intestinal continuity after a coloanal anastomosis is associated with diminished quality of life.
Keywords
Adenocarcinoma/radiotherapy, Adenocarcinoma/surgery, Adult, Aged, Aged, 80 and over, Anal Canal/surgery, Anastomosis, Surgical, Colon/surgery, Colostomy, Combined Modality Therapy, Female, Humans, Male, Middle Aged, Postoperative Complications, Quality of Life, Questionnaires, Rectal Neoplasms/radiotherapy, Rectal Neoplasms/surgery
Pubmed
Web of science
Open Access
Yes
Create date
07/10/2014 14:10
Last modification date
20/05/2022 10:34
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