Long-term functional and quality of life outcomes after coloanal anastomosis for distal rectal cancer.

Details

Serval ID
serval:BIB_184E117347DC
Type
Article: article from journal or magazin.
Collection
Publications
Title
Long-term functional and quality of life outcomes after coloanal anastomosis for distal rectal cancer.
Journal
Diseases of the Colon and Rectum
Author(s)
Hassan I., Larson D.W., Cima R.R., Gaw J.U., Chua H.K., Hahnloser D., Stulak J.M., O'Byrne M.M., Larson D.R., Wolff B.G., Pemberton J.H.
ISSN
0012-3706 (Print)
ISSN-L
0012-3706
Publication state
Published
Issued date
2006
Volume
49
Number
9
Pages
1266-1274
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
PURPOSE: This study was designed to evaluate the long-term functional and quality-of-life outcomes of patients after coloanal anastomosis for distal rectal cancer.
METHODS: A total of 192 patients underwent coloanal anastomosis between 1982 and 2001 at two tertiary referral institutions. Standardized and validated questionnaires to assess functional and quality-of-life outcomes were mailed to 151 patients, of which 121 patients responded (median follow-up, 65 months).
RESULTS: Patients receiving pelvic radiotherapy had more bowel function problems than patients who did not receive pelvic radiotherapy. No significant differences in relevant functional and quality-of-life outcomes were seen among patients who received preoperative or postoperative pelvic radiotherapy. Patients requiring permanent diversion as a result of complications of the surgery had decreased quality of life.
CONCLUSIONS: Coloanal anastomosis for distal rectal cancer has favorable long-term outcomes. Pelvic radiotherapy has an adverse effect on subsequent bowel function (whether given preoperatively or postoperatively) in patients who maintain intestinal continuity. Loss of intestinal continuity after a coloanal anastomosis is associated with diminished quality of life.
Keywords
Adenocarcinoma/radiotherapy, Adenocarcinoma/surgery, Adult, Aged, Aged, 80 and over, Anal Canal/surgery, Anastomosis, Surgical, Colon/surgery, Colostomy, Combined Modality Therapy, Female, Humans, Male, Middle Aged, Postoperative Complications, Quality of Life, Questionnaires, Rectal Neoplasms/radiotherapy, Rectal Neoplasms/surgery
Pubmed
Web of science
Create date
07/10/2014 14:10
Last modification date
20/08/2019 12:48
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