Abnormal sensitivity to negative feedback in late-life depression.

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State: Public
Version: author
Serval ID
serval:BIB_183B1A07F5B6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Abnormal sensitivity to negative feedback in late-life depression.
Journal
Psychiatry and Clinical Neurosciences
Author(s)
von Gunten A., Herrmann F.R., Elliott R., Duc R.
ISSN
1440-1819 (Electronic)
ISSN-L
1323-1316
Publication state
Published
Issued date
2011
Peer-reviewed
Oui
Volume
65
Number
4
Pages
333-340
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
AIMS: The purpose of the present study was to probe sensitivity to potentially misleading negative feedback on cognitive tasks as a possible mechanism of cognitive impairment in elderly patients with mild depression.
METHODS: A total of 22 mildly depressed elderly subjects were compared to 22 healthy controls, using a computerized Tower-of-London task.
RESULTS: Failure and magnitude of failure were significantly worse after negative but not positive feedback. Depression predicted failure after negative feedback but not the magnitude of failure. Neither failure nor magnitude of failure increased as a consequence of repeated negative feedback.
CONCLUSIONS: Altered sensitivity to negative feedback occurs in mild late-life unipolar depression and may represent a subtle context-specific phenomenon.
Keywords
Aged, Aged, 80 and over, Cognition/physiology, Depressive Disorder/psychology, Feedback, Psychological/physiology, Female, Humans, Male, Neuropsychological Tests
Pubmed
Web of science
Create date
23/06/2011 15:29
Last modification date
20/03/2020 7:08
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