Dosimetry in MARS spectral CT: TOPAS Monte Carlo simulations and ion chamber measurements.

Details

Serval ID
serval:BIB_181B59B2AC09
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Dosimetry in MARS spectral CT: TOPAS Monte Carlo simulations and ion chamber measurements.
Journal
Australasian physical & engineering sciences in medicine
Author(s)
Lu G., Marsh S., Damet J., Carbonez P., Laban J., Bateman C., Butler A., Butler P.
ISSN
1879-5447 (Electronic)
ISSN-L
0158-9938
Publication state
Published
Issued date
06/2017
Peer-reviewed
Oui
Volume
40
Number
2
Pages
297-303
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Spectral computed tomography (CT) is an up and coming imaging modality which shows great promise in revealing unique diagnostic information. Because this imaging modality is based on X-ray CT, it is of utmost importance to study the radiation dose aspects of its use. This study reports on the implementation and evaluation of a Monte Carlo simulation tool using TOPAS for estimating dose in a pre-clinical spectral CT scanner known as the MARS scanner. Simulated estimates were compared with measurements from an ionization chamber. For a typical MARS scan, TOPAS estimated for a 30 mm diameter cylindrical phantom a CT dose index (CTDI) of 29.7 mGy; CTDI was measured by ion chamber to within 3% of TOPAS estimates. Although further development is required, our investigation of TOPAS for estimating MARS scan dosimetry has shown its potential for further study of spectral scanning protocols and dose to scanned objects.

Keywords
Animals, Computer Simulation, Humans, Ions, Mice, Monte Carlo Method, Phantoms, Imaging, Polymethyl Methacrylate/chemistry, Radiation Dosage, Radiometry/instrumentation, Tomography, X-Ray Computed/instrumentation, X-Rays, Dosimetry, Ionization chamber, MARS, Medipix, Monte Carlo simulation, Spectral computed tomography, TOPAS
Pubmed
Web of science
Create date
28/02/2017 18:51
Last modification date
20/08/2019 12:48
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