Antimicrobial susceptibility and frequency of occurrence of clinical blood isolates in Europe from the SENTRY antimicrobial surveillance program, 1997 and 1998.

Details

Serval ID
serval:BIB_17485
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Antimicrobial susceptibility and frequency of occurrence of clinical blood isolates in Europe from the SENTRY antimicrobial surveillance program, 1997 and 1998.
Journal
Clinical Infectious Diseases
Author(s)
Fluit A.C., Jones M.E., Schmitz F.J., Acar J., Gupta R., Verhoef J.
ISSN
1058-4838
Publication state
Published
Issued date
2000
Volume
30
Number
3
Pages
454-460
Language
english
Abstract
As part of the European arm of the SENTRY Antimicrobial Surveillance Program, 25 European university hospitals referred 9613 blood isolates for in vitro testing against >20 antimicrobial agents. Escherichia coli, Staphylococcus aureus, coagulase-negative Staphylococcus, Pseudomonas aeruginosa, and Klebsiella pneumoniae were the 5 most frequent isolates and accounted for two-thirds of all referrals, with minor regional variation. Of these, approximately 0.36% of E. coli and 16.7% of K. pneumoniae isolates proved to be potential extended-spectrum beta-lactamase producers, and their incidence clearly varied regionally. Quinolone resistance was detected among gram-negative species; in particular, P. aeruginosa and Acinetobacter species. Considerable regional variation was observed in the incidences of methicillin resistance in S. aureus and penicillin resistance in Streptococcus pneumoniae. The incidence of vancomycin resistance in enterococci was relatively low overall and primarily associated with Enterococcus faecium. However, extrapolation of these data to smaller and nonteaching hospitals should be undertaken with caution, since resistance rates may be lower in these facilities.
Keywords
Anti-Bacterial Agents/pharmacology, Bacteremia/epidemiology, Bacteremia/microbiology, Bacteria/classification, Bacteria/drug effects, Community-Acquired Infections/epidemiology, Community-Acquired Infections/microbiology, Cross Infection/epidemiology, Cross Infection/microbiology, Drug Resistance, Microbial, Europe/epidemiology, Hospitals, University, Humans, Microbial Sensitivity Tests, Sentinel Surveillance
Pubmed
Web of science
Open Access
Yes
Create date
19/11/2007 12:11
Last modification date
20/08/2019 12:47
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