The main argument of this paper is that a holistic view together with a multidimensional simulation tool outperforms the conventional means of logistics planning. By comprising the customer requirements, measurement of economical performance, supply constraints, physical material flows and ecological assessment the tool described provides the company management with a fast and reliable appraisal of various logistics scenarios of the future. Questions such as where to store, produce or locate production and under which exogenous circumstances will receive analyzed answers. Technical solution based on high-speed computing enables the evaluation of detailed and accurate models with voluminous data in reasonable response times. All this is integrated with a high-standard graphical user interface with interactive presentation and analysis of results. The paper discusses the applied approach and the solution structure of the system. The work is associated with an ongoing Esprit III project #8615—LOCOMOTIVE (Logistic Chain Multidimensional Design Toolbox with Environmental Assessment).