The B cell antigen CD75 is a cell surface sialytransferase.

Details

Serval ID
serval:BIB_16CF55763CCE
Type
Article: article from journal or magazin.
Collection
Publications
Title
The B cell antigen CD75 is a cell surface sialytransferase.
Journal
The Journal of experimental medicine
Author(s)
Stamenkovic I., Asheim H.C., Deggerdal A., Blomhoff H.K., Smeland E.B., Funderud S.
ISSN
0022-1007 (Print)
ISSN-L
0022-1007
Publication state
Published
Issued date
01/08/1990
Peer-reviewed
Oui
Volume
172
Number
2
Pages
641-643
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
In this work we have isolated a cDNA clone encoding the B cell antigen CD75. The amino acid sequence of CD75 is shown to be identical to that of human alpha 2,6 sialyltransferase, believed to be primarily associated with the Golgi complex. This is the first demonstration of cell surface expression of sialytransferase which, in B cells, may play an important role in intercellular adhesion and antigen presentation events.
Keywords
Amino Acid Sequence, Animals, B-Lymphocytes/enzymology, B-Lymphocytes/immunology, Base Sequence, Burkitt Lymphoma, Cell Line, DNA, Neoplasm/genetics, DNA, Neoplasm/isolation & purification, Gene Library, Glycosylation, Humans, Molecular Sequence Data, RNA, Neoplasm/genetics, RNA, Neoplasm/isolation & purification, Sialyltransferases/genetics, Transfection
Pubmed
Web of science
Open Access
Yes
Create date
29/01/2008 19:36
Last modification date
02/07/2024 14:36
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