Comparison of quality of life evaluated by SF-36 and DLQI in multibacillary and paucibacillary leprosy patients from Sao Paulo, Brazil.

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State: Public
Version: Final published version
License: All rights reserved
Serval ID
serval:BIB_163324B9F2F6
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Comparison of quality of life evaluated by SF-36 and DLQI in multibacillary and paucibacillary leprosy patients from Sao Paulo, Brazil.
Journal
International journal of dermatology
Author(s)
Guimenes Albuquerque R., Grüdtner Buratto G., Hirotsu C., Maeda S.M., Floriano M.C., Levy Andersen M., Tufik S., Tomimori J.
ISSN
1365-4632 (Electronic)
ISSN-L
0011-9059
Publication state
Published
Issued date
12/2019
Peer-reviewed
Oui
Volume
58
Number
12
Pages
1415-1422
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Dermatological diseases have a negative impact on quality of life (QoL), affecting mental and physical health. Leprosy patients usually present with a worse QoL compared with those affected by other conditions. Reactions, neural damage, and pain are some of the consequences that contribute to the lower QoL. However, due to the wide spectrum of the disease, symptoms vary according to leprosy's subtype. This study aimed to compare the QoL between paucibacillary and multibacillary leprosy patients. Individuals were also compared considering the presence of reactions and a correlation between questionnaires was performed.
A total of 104 patients with leprosy aged 18 years old and over were selected. QoL was assessed by the Brazilian-Portuguese validated versions of the Medical Outcomes Study 36-item short-form health survey (SF-36) and the Dermatology Life Quality Life Index (DLQI).
Multibacillary patients showed a more impaired physical function, worse bodily pain, lower score of SF-36, and higher interference of skin on the performance of daily activities when compared to the paucibacillary group. Individuals without reactions presented lower bodily pain and less effect of the skin on clothing choices compared to those with reactions. The SF-36 domains exhibited weak correlations with most DLQI questions, and the linear regression model showed that 32% of changes in QoL were related to the skin aspect.
Multibacillary leprosy patients have a worse QoL when compared to paucibacillary patients. Reactions played a small role in the QoL of our cohort of patients.
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Web of science
Create date
17/12/2019 16:06
Last modification date
01/08/2020 5:19
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