Squamous cell carcinoma of the head and neck - screening in patients who misuse alcohol and tobacco in Switzerland: a prospective pilot study.

Details

Serval ID
serval:BIB_16216F70E2A1
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Squamous cell carcinoma of the head and neck - screening in patients who misuse alcohol and tobacco in Switzerland: a prospective pilot study.
Journal
The British journal of oral & maxillofacial surgery
Author(s)
Mermod M., Adam A., Clair C., Faouzi M., Simon C., Daeppen J.B., Bertholet N., Monnier Y.
ISSN
1532-1940 (Electronic)
ISSN-L
0266-4356
Publication state
Published
Issued date
12/2019
Peer-reviewed
Oui
Volume
57
Number
10
Pages
1053-1057
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Squamous cell carcinoma (SCC) of the head and neck is the sixth most common cancer worldwide. It is preceded by early asymptomatic lesions which, if identified early enough and removed, would prevent malignant transformation or avoid delaying diagnosis to advanced stages. Our aim was to evaluate the feasibility of a screening programme for SCC of the head and neck in a group of high-risk patients, and to investigate their addiction profile. Patients admitted to an inpatient alcohol addiction centre (n=101) were prospectively enrolled and asked to fill in a questionnaire about their use of tobacco and alcohol, and the presence of warning symptoms for SCC of the head and neck from 23 June 2014 to 21 January2016. Participants in the study had a physical examination by an alcohol addiction physician followed by a full examination of the head and neck by an otorhinolaryngologist to rule out premalignant or malignant lesions of the upper aerodigestive tract. Of the 101 patients, 62 (60%) had at least one warning symptom. Alcohol addiction physicians identified leukoplakia in six (6%) and erythroplakia in two. No pre-malignant or malignant lesions were confirmed on examination by the otolaryngologist. We were unable to draw conclusions about the cost-effectiveness or the yield of the screening programme. Despite our negative findings, we may need further investigation to clarify the relevance of such a programme on health-related outcome given the high compliance rate and minimal delay that was achieved by taking advantage of an in-patient alcohol rehabilitation centre.
Keywords
Alcohol Drinking, Carcinoma, Squamous Cell/diagnosis, Head and Neck Neoplasms/diagnosis, Humans, Inpatients, Mass Screening, Pilot Projects, Prospective Studies, Smoking, Squamous Cell Carcinoma of Head and Neck/diagnosis, Substance Abuse Treatment Centers, Switzerland, Tobacco, Alcohol, Screening, head and neck squamous cell carcinoma
Pubmed
Web of science
Create date
10/10/2019 20:59
Last modification date
27/03/2020 6:26
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