La polypill: entre mythes et réalité dans le traitement du diabète sucré [The Polypill: between myths and reality in the treatment of type 2 diabetes mellitus].

Details

Serval ID
serval:BIB_160A96DE5847
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
La polypill: entre mythes et réalité dans le traitement du diabète sucré [The Polypill: between myths and reality in the treatment of type 2 diabetes mellitus].
Journal
Revue Médicale Suisse
Author(s)
Ruiz J., Egli M.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
05/2006
Volume
2
Number
68
Pages
1480-2, 1484-5
Language
french
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Abstract
The Polypill: between myths and reality in the treatment of type 2 diabetes mellitus The concept of "Polypill" was developed from modeling analyses and the data were extracted from randomized-control trials and epidemiological studies. This "Polypill" should be a combination of three antihypertensive drugs associated to aspirin, a statin and folic acid. This "Polypill" would allow to reduce of more than 80% the cardiovascular events. The original publication suggests that all subjects of more than 55 years could benefit from this magic pill. Numerous positive and negative reactions showed themselves further to this publication. Other approaches based on the change of lifestyle seem so effective. Nevertheless, to have a really effective approach the therapeutic educational dimension should be also included in the basic strategy.
Keywords
Antihypertensive Agents/therapeutic use, Aspirin/therapeutic use, Cardiovascular Diseases/prevention & control, Diabetes Mellitus, Type 2/drug therapy, Drug Combinations, Folic Acid/therapeutic use, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use, Platelet Aggregation Inhibitors/therapeutic use
Pubmed
Create date
03/03/2008 15:15
Last modification date
20/08/2019 12:45
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