Red meat intake and cancer risk: a study in Italy.

Details

Serval ID
serval:BIB_14337
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Red meat intake and cancer risk: a study in Italy.
Journal
International Journal of Cancer. Journal International Du Cancer
Author(s)
Tavani A., La Vecchia C., Gallus S., Lagiou P., Trichopoulos D., Levi F., Negri E.
ISSN
0020-7136 (Print)
ISSN-L
0020-7136
Publication state
Published
Issued date
2000
Volume
86
Number
3
Pages
425-428
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Meat intake has been positively associated with risk of digestive tract cancers in several epidemiological studies, while data on the relation of meat intake with cancer risk at most other sites are inconsistent. The overall data set, derived from an integrated series of case-control studies conducted in northern Italy between 1983 and 1996, included the following incident, histologically confirmed neoplasms: oral cavity, pharynx and esophagus (n = 497), stomach (n = 745), colon (n = 828), rectum (n = 498), liver (n = 428), gallbladder (n = 60), pancreas (n = 362), larynx (n = 242), breast (n = 3,412), endometrium (n = 750), ovary (n = 971), prostate (n = 127), bladder (n = 431), kidney (n = 190), thyroid (n = 208), Hodgkin's disease (n = 80), non-Hodgkin's lymphomas (n = 200) and multiple myelomas (n = 120). Controls were 7,990 patients admitted to hospital for acute, non-neoplastic conditions unrelated to long-term modifications in diet. The multivariate odds ratios (ORs) for the highest tertile of red meat intake (>/=7 times/week) compared with the lowest (</=3 times/week) were 1.6 for stomach, 1.9 for colon, 1.7 for rectal, 1.6 for pancreatic, 1.6 for bladder, 1.2 for breast, 1.5 for endometrial and 1.3 for ovarian cancer. ORs showed no significant heterogeneity across strata of age at diagnosis and sex. No convincing relation with red meat intake emerged for cancers of the oral cavity, pharynx and esophagus, liver, gallbladder, larynx, kidney, thyroid, prostate, Hodgkin's disease, non-Hodgkin's lymphomas and multiple myeloma. For none of the neoplasms considered was there a significant inverse relationship with red meat intake. Thus, reducing red meat intake might lower the risk for several common neoplasms.
Keywords
Adult, Aged, Case-Control Studies, Databases, Factual, Diet, Female, Humans, Italy/epidemiology, Male, Meat, Middle Aged, Neoplasms/epidemiology, Neoplasms/etiology, Risk
Pubmed
Web of science
Open Access
Yes
Create date
19/11/2007 12:06
Last modification date
20/08/2019 12:42
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