Sex differences in colorectal cancer mortality in Europe, 1955-1996.

Details

Serval ID
serval:BIB_14301
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Sex differences in colorectal cancer mortality in Europe, 1955-1996.
Journal
European Journal of Cancer Prevention
Author(s)
Fernandez E., Bosetti C., La Vecchia C., Levi F., Fioretti F., Negri E.
ISSN
0959-8278 (Print)
ISSN-L
0959-8278
Publication state
Published
Issued date
2000
Volume
9
Number
2
Pages
99-104
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Colorectal cancer is the leading cancer in non-smokers in Western countries, and over the last decades its trends have been generally more favourable for women than for men. Possible explanations of the sex differentials in colorectal cancer relate to different exposure to exogenous hormones and to other risk factors including diet, physical activity and alcohol drinking. The objective of this investigation was to systematically analyse the trends in colorectal cancer mortality sex ratios in major European countries over the last four decades. Trends in death certification rates from colorectal cancer over the period 1955-1996 were analysed for 20 European countries (excluding the former Soviet Union and a few of the smaller countries). In all countries, the mortality sex ratios (M/F) were around or slightly above unity in the 1950s, and systematically increased to approach 1.5 in the 1990s. The extent of the rises varied across countries, ranging between + 0.8% in Germany, + 9.7% in Sweden, and + 12.1% in Denmark (the lowest increases) to + 65.3% in Spain, + 56.2% in Portugal, and + 50.4% in Hungary (the highest ones). Mortality sex ratios in Europe show more favourable trends for females, which may be attributable, in part, to the introduction of exogenous hormones in the late 1950s and 1960s, and, in part, to differential sex exposure to major environmental risk factors.
Keywords
Adult, Aged, Colorectal Neoplasms/mortality, Colorectal Neoplasms/prevention &amp, control, Diet, Environmental Exposure/adverse effects, Type="Geographic">Europe/epidemiology, Exercise, Female, Hormone Replacement Therapy, Humans, Male, Middle Aged, Risk Factors, Sex Factors, Sex Ratio, Statistics, Nonparametric
Pubmed
Web of science
Create date
19/11/2007 12:06
Last modification date
20/08/2019 12:42
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